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Showing 7 events.
  • Data-driven modelling of intercellular interactions in the tumour microenvironment

    25 January 2023

    ELIXIR node event
  • Exploring reproducible and reusable systems biology models with BioModels

    1 February 2023

    ELIXIR node event
  • Integrated Modeling and Optimization (Fundamental)

    12 - 16 December 2022

    Wageningen Campus, Netherlands

    ELIXIR node event
  • Constraint-based modeling: Introduction and advanced topics

    13 - 17 February 2023

    Wageningen Campus, Netherlands

    ELIXIR node event
  • Introduction to Linear Modelling with R (ONLINE LIVE TRAINING)

    7 February 2023

    Cambridge, United Kingdom

    ELIXIR node event
  • PerMedCoE summer school: from pathway modelling tools to cell-level simulations

    25 - 30 June 2023

    ELIXIR node event
  • 6th Advanced in silico Drug Design workshop/challenge 2023

    30 January - 3 February 2023

    Olomouc

    ELIXIR node event
Showing 30 materials out of 129. View all results.
BioModels

This quick tour provides a brief introduction to EMBL-EBI’s resource of mathematical models of biological/biomedical systems.

Scientific topics: Systems biology

Keywords: Systems modelling, Mathematical modelling, Modelling

Resource type: e-learning

Model Creation using COPASI

A tutorial on how to create kinetic models with COPASI. Covers the basics of creating models, including definition of new rate laws, etc.

COPASI logo

Scientific topics: Simulation experiment

Operations: Modelling and simulation, Visualisation

Keywords: SystemsBiology, ComputationalBiology, Computational modelling, modeling, Biomodelling, Model, Kinetic modeling, COPASI

Resource type: Video

BioSimulations tutorial and help

BioSimulations is a web application for sharing and re-using biomodels, simulations, and visualizations of simulations results. BioSimulations supports a wide range of modeling frameworks (e.g., kinetic, constraint-based, and logical modeling), model formats (e.g., BNGL, CellML, SBML), and...

Scientific topics: Computational biology, Systems biology, Simulation experiment

Operations: Visualisation, Modelling and simulation

Keywords: SystemsBiology, ComputationalBiology, Computational modelling, Modeling, Biomodelling, Model, Kinetic modeling, SED-ML, COMBINE

Resource type: Documentation

Graphical & Computational Modelling of Biological Pathways

  1. Introduction

  2. Many Views of A Pathway(Lecture)

  3. Pathway Models & Pathway Types (Lecture)

  4. Sources of ‘Pathway Data’ (Lecture)

  5. Issues (Lecture)

  6. SBGN (Lecture)

  7. mEPN (Lecture)

  8. Practical Session: Pathway to Pathway Construction - yED(1)

  9. Practical...

Keywords: Graphical modelling, Computational modelling, Roslin Institute

Metabolic Control Analysis in COPASI

A tutorial on Metabolic Control Analysis and how to apply it to kinetic models with the software COPASI.

COPASI logo

Scientific topics: Simulation experiment, Systems biology

Operations: Modelling and simulation, Analysis, Visualisation

Keywords: SystemsBiology, ComputationalBiology, Computational modelling, Kinetic modeling, COPASI

Resource type: Video

Time Course Simulation in COPASI

A short tutorial on how to carry out time course simulations based on ODEs with the software COPASI.

COPASI logo

Scientific topics: Simulation experiment

Operations: Modelling and simulation, Visualisation

Keywords: SystemsBiology, ComputationalBiology, Computational modelling, Kinetic modeling, COPASI

Resource type: Video

Parameter Scanning and Sampling in COPASI

A video tutorial for the simulation software COPASI, showing how to create sequences of simulations that scan values of various parameters, or that sample those parameters at random.

COPASI logo

Scientific topics: Simulation experiment

Operations: Modelling and simulation, Analysis, Visualisation

Keywords: SystemsBiology, ComputationalBiology, Computational modelling, Kinetic modeling, COPASI

Resource type: Video

runBioSimulations tutorial and help

runBioSimulations is a web application for executing a broad range of modeling studies and visualizing their results. runBioSimulations uses BioSimulators to supports a broad range of modeling frameworks (e.g., logical, constraint-based, kinetic), simulation algorithms (e.g., CVODE, FBA, SSA),...

Scientific topics: Systems biology, Computational biology, Simulation experiment

Operations: Modelling and simulation

Keywords: biosimulators, COMBINE, OMEX, SED-ML, Modeling, dynamic simulations, SBML, BNGL

Resource type: Tutorial, Documentation

RRegrs package

This tutorial explains how to use a collection of R regression tools for estimating the optimal model via a fully validated procedure.

Keywords: Regression Models

Introduction to Mixed Models

  1. Introduction

  2. What Are Mixed Models?

  3. Potential Advantages of Mixed Models

  4. Historical Perspective

  5. Example 1: Biological & Technical Replicates

  6. Example 2: Rabbit Inspiration Time – Sources of Variation

  7. Non-Normal Data

  8. Example 3: Non-normal data

9....

Keywords: Mixed models, Roslin Institute

Introduction to Statistical Modelling

  1. Introduction

  2. One-Way Analysis of Variance (ANOVA) Recap

  3. Two-Way ANOVA - Assessing Two Effects in Same Model

  4. Two-Way ANOVA - Allowing for Structure in The Data

  5. Paired T-Test Using Two-Way ANOVA & ANOVA With More Effects

  6. Regression Recap

  7. General Linear...

Keywords: Statistical modelling, Roslin Institute

Graphical & Computational Modelling of Biological Pathways

  1. Introduction

  2. Many Views of A Pathway(Lecture)

  3. Pathway Models & Pathway Types (Lecture)

  4. Sources of ‘Pathway Data’ (Lecture)

  5. Issues (Lecture)

  6. SBGN (Lecture)

  7. mEPN (Lecture)

  8. Practical Session: Pathway to Pathway Construction - yED(1)

  9. Practical...

Keywords: Graphical modelling, Roslin Institute

PSLS20 - Practical Statistics for the Life Sciences (2020)

This intermediate level course is one of our Foundations courses. It covers essential statistical concepts and methods for extracting insights from empirical data in the life sciences. The course positions applied statistics, starting from important aspects of experimental design and data...

Keywords: Statistics, General Linear Models

Resource type: Documentation, Exercise, Handout, Scripts

Introduction to 3D-Structure Visualization and Homology Modeling using the Swiss-Model Workspace

The goal of this course is to expose the participants to 3-dimensional structures of proteins. Analysis and visualization software (DeepView) will be used to display, analyze, compare and interpret protein structures. The second part of the course is dedicated to protein structure prediction...

BioSimulators tutorial and help

BioSimulators is a registry of containerized biosimulation tools that provide consistent command-line interfaces. The BioSimulations web application helps investigators browse this registry to find simulation tools that have the capabilities (supported modeling frameworks, simulation algorithms,...

Scientific topics: Systems biology, Computational biology, Simulation experiment

Operations: Modelling and simulation

Keywords: Modeling, biomodel, dynamic simulations, COMBINE, OMEX, SED-ML, SBML, BNGL

Resource type: Tutorial, Documentation

Steady State Analysis in COPASI

A short tutorial on how to carry out steady state simulations with the software COPASI.

COPASI logo

Scientific topics: Systems biology, Computational biology, Simulation experiment

Operations: Modelling and simulation, Visualisation

Resource type: Video

DE-Sim examples, tutorials, and documentation

DE-Sim is an open-source, Python-based object-oriented discrete-event simulation (DES) tool that makes it easy to use large, heterogeneous datasets and high-level data science tools such as NumPy, Scipy,...

Scientific topics: Simulation experiment, Computer science, Mathematics, Computational biology

Operations: Modelling and simulation, Visualisation

Keywords: data-driven modeling, Computational modelling, discrete-event simulation, DES, object-oriented programming, Python, data visualization, Data Science

Resource type: examples, Tutorial, Jupyter notebook, API reference

BioExcel Building Blocks (BioBB) Training Material

BioExcel Building Blocks (BioBB) is a software library for interoperable biomolecular simulation workflows, built within the BioExcel CoE project, and developed following best practices on software development aligned with ELIXIR.

Keywords: molecular dynamics, Docking, Modeling, life sciences

Resource type: Jupyter notebook

FAIRification & Data modelling

Wikidata
fairification

Keywords: FAIR, linked data, ontologies, metadata

Resource type: Slides

Genome Properties

Genome Properties allows you to infer the presence of pathways and systems within a species, based on the occurrence of a set of underlying molecular markers.

Keywords: Functional annotation, Protein signature models, Phylogenetic profiling

Resource type: e-learning

Datanator tutorial

Datanator is an integrated database of genomic and biochemical data designed to help investigators find data about specific molecules and reactions in specific organisms and specific environments for meta-analyses and mechanistic models. Datanator currently includes metabolite concentrations, RNA...

Scientific topics: Molecular biology, Cell biology, Systems biology, Bioinformatics, Omics

Operations: Query and retrieval, Filtering

Keywords: genomics, Proteomics, transcriptomics, Metabolomics, reaction kinetics, Kinetic modeling, meta analysis

Resource type: Tutorial

An Introduction to Mathematical Modelling

This course provides an introduction to the concepts of modelling biological systems. It is intended for biologists who have no experience in modelling but would like to know how it might apply to their area of research. The course provides a complete background to the history of modelling and...

Model organism analysis using Intermine

Poster presented at 3rd BiVi in April 2017.InterMine is an open source data warehouse based in the University of Cambridge. We integrate data from disparate sources and provide a single unified interface, allowing you to access your data via an easy-to-use webapp or API. InterMine has over 30...

Keywords: Cells and Organisms

Resource type: Poster

Signalling Networks: From Data to Modelling

What is the course about?
Signalling pathways and networks are very important to regulate and control cellular processes, cell fate, and their malfunctions often lead to diseases, such as cancer or diabetes. This course provides an introductory overview of the most useful resources and tools to...

Keywords: Signalling

Introduction to qualitative modelling with MaBoSS

Boolean modelling uses a simple representation of biological entities as either active or inactive, and describes their relations with logical formulas. MaBoSS extends Boolean modelling by adding a notion of continuous time, with the introduction of rates of (in)activation. This enable the...

Scientific topics: Simulation experiment, Personalised medicine, Molecular interactions, pathways and networks, Statistics and probability

Operations: Modelling and simulation

Keywords: HPC, Biomodelling, cell simulations, Boolean

Resource type: Webinar

Mathematics of life: Modelling molecular mechanisms

This course will provide participants with an introduction and hands-on training on modelling approaches, tools and resources used in systems biology as well as touch on network analysis.

Resource type: Course materials

Introduction to qualitative modelling with MaBoSS

Boolean modelling uses a simple representation of biological entities as either active or inactive, and describes their relations with logical formulas. MaBoSS extends Boolean modelling by adding a notion of continuous time, with the introduction of rates of (in)activation. This enable the...

Scientific topics: Systems biology

Resource type: Recorded webinar

Jaqpot Hackathon - Training materials

Under the subtitle “Take your research from the bench to the community by making your models available as a web service”, attendees learned how to use the Jaqpot suite and python to go from data to model, starting from a common CSV file.

Jaqpot is a computational platform for in silico...

Keywords: nanoinformatics, toxicity prediction, e-tools, Modeling, data FAIRness

Analysis of huge metabolic models with COBREXA.jl

COBREXA.jl is a new software package to enable the analysis and simulation of large metabolic models by taking advantages of modern HPC infrastructure. Mainly, it advanced the scalability of constraint-based method, using the Julia programing language and its mathematic ecosystem as a base...

Scientific topics: Simulation experiment

Keywords: cell-level simulations, HPC, Biomodelling

Resource type: Webinar

Hands-on for 'Species distribution modeling' tutorial

The questions this addresses are:
- How to build & evaluate a niche model, visualize and project it ?

The objectives are:
- Find and download occurrences data from GBIF
- Find and download environmental data
- Process both occurrences and environmental
- Partition occurrence data
-...

Scientific topics: Ecology

Keywords: ecology, interactive-tools, modeling, gbif, species populations EBV class

Resource type: hands-on tutorial

Showing 11 content providers.
  • BioExcel

    BioExcel is a Centre of Excellence for Computational Biomolecular Research set up to support...

    0 upcoming events (11 past events)
    BioExcel https://tess.elixir-europe.org/content_providers/bioexcel BioExcel is a Centre of Excellence for Computational Biomolecular Research set up to support academia and industry in the use of high-end computing in biomolecular research. /system/content_providers/images/000/000/053/original/BioExcel_logo_payoff.png?1470306206
  • OpenRiskNet

    The main objective of OpenRiskNet is to develop an open e-Infrastructure providing resources and...

    0 upcoming events (10 past events)
    OpenRiskNet https://tess.elixir-europe.org/content_providers/openrisknet The main objective of OpenRiskNet is to develop an open e-Infrastructure providing resources and services to a variety of communities requiring risk assessment, including chemicals, cosmetic ingredients, therapeutic agents and nanomaterials. OpenRiskNet is * a virtual research environment for predictive toxicology and chemical and nanomaterial risk assessment, * harmonising access to data and facilitating interoperability of software, * easily deployable to single computers, public and in-house cloud solutions, * addressing the needs of industry and academic researchers, risk assessors, regulators and informed public. OpenRiskNet (Grant Agreement 731075) is a 3-years project funded by the European Commission within the Horizon2020 Programme /system/content_providers/images/000/000/097/original/ORN-Web_Logo3.png?1533933310
  • PerMedCoE

    PerMedCoE is the HPC/Exascale Centre of Excellence for Personalised Medicine in Europe.

    10 training materials
    PerMedCoE https://tess.elixir-europe.org/content_providers/permedcoe PerMedCoE is the HPC/Exascale Centre of Excellence for Personalised Medicine in Europe. /system/content_providers/images/000/000/637/original/LOGO_PerMedCoE.jpg?1636473064
  • Genome 3D

    Genome3D provides consensus structural annotations and 3D models for sequences from model...

    8 training materials
    Genome 3D https://tess.elixir-europe.org/content_providers/genome-3d Genome3D provides consensus structural annotations and 3D models for sequences from model organisms, including human. These data are generated by several UK based resources in the Genome3D consortium: SCOP, CATH, SUPERFAMILY, Gene3D, FUGUE, THREADER, PHYRE. /system/content_providers/images/000/000/006/original/images?1469458224
  • FAIRDOM

    Research Infrastructure supporting life scientists in managing their data and models FAIRly....

    1 training material
    0 upcoming events (2 past events)
    FAIRDOM https://tess.elixir-europe.org/content_providers/fairdom Research Infrastructure supporting life scientists in managing their data and models FAIRly. Specifically designed for interdisciplinary research such as systems biology, systems medicine, and synthetic biology. /system/content_providers/images/000/000/100/original/Screen_Shot_2018-09-06_at_15.54.17.png?1536245244
  • Open Science MOOC

    Open Science MOOC is a mission-driven project to help make ‘Open’ the default setting for all...

    1 training material
    Open Science MOOC https://tess.elixir-europe.org/content_providers/open-science-mooc Open Science MOOC is a mission-driven project to help make ‘Open’ the default setting for all global research. We want to help create a welcoming and supporting community, with good tools, teachers, and role-models, and built upon a solid values-based foundation of freedom and equitable access to research. /system/content_providers/images/000/000/101/original/31343113?1536821365
  • Biomedical Sciences Research Center "Alexander Fleming"

    The Biomedical Sciences Research Center "Alexander Fleming" is a non-profit research organisation...

    1 training material
    Biomedical Sciences Research Center "Alexander Fleming" https://tess.elixir-europe.org/content_providers/biomedical-sciences-research-center-alexander-fleming The Biomedical Sciences Research Center "Alexander Fleming" is a non-profit research organisation based in Vari, Athens, Greece. Since the beginning of its operations in 1998, the Center develops basic as well as translational and applied research programs at the cutting edge of modern biomedical sciences. Currently, the Center hosts 14 research groups distributed in 4 Institutes (Immunology, Molecular Oncology, Molecular Biology and Genetics, Cellular & Developmental Biology). Over the short period since its establishment, BSRC "Alexander Fleming" has gained extensive visibility in the European science arena. Fleming researchers have established transgenic animal models for rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis and these models have served as a basis for multiple collaborations with the international biopharmaceutical industry in the evaluation of novel therapeutic compounds, or as tools for collaborative R&D. The Center is equipped with state-of-the-art Core Units which include: an Expression Profiling Facility, a Flow Cytometry Facility, a Protein Chemistry Lab, a Transgenics and gene targeting Unit, and a BioIT Unit, all of which serve internal collaborations, as well as external partners in academia and industry. The Center also runs an Innovation and Enterprise Unit that facilitates the protection and exploitation of the Center’s research and technologies. Fleming operates its own Animal House, which can house up to 15,000 mice, and has its own complete mouse histopathology unit. Fleming’s Animal house (certified with ISO 9001) provides husbandry of animals and services to the biomedical research community since 2001. It covers an area of approximately 600 m2 within the Center and is equipped with highly automated systems that provide the best possible conditions for mouse reproduction and maintenance. Its main activity is the reproduction and maintenance of mice stocks either of inbred strains or genetically engineered mice, such as transgenic and knockout mouse lines, as well as chemically induced mutants developed by Fleming researchers. The Animal House has a capacity to house more than 18,000 mice and is currently the largest Mouse Unit in Greece in terms of number and variety of mice. The Facility became a full member of EMMA in 2009. Main areas of research: Functional genomics and proteomics; Molecular and cellular immunology; Animal models of human disease; Transcriptional and post-transcriptional mechanisms of gene regulation; DNA repair; Stem Cell differentiation; Epigenetics; Learning and memory; ECM biology. Fields of excellence: Molecular mechanisms of disease (inflammation, cancer, metabolic syndrome, CNS disorders). /system/content_providers/images/000/000/051/original/logo.png?1469458221
  • eNanoMapper

    eNanoMapper developed a computational infrastructure for toxicological data management of...

    10 training materials
    eNanoMapper http://tess.elixir-uk.org/content_providers/enanomapper eNanoMapper developed a computational infrastructure for toxicological data management of engineered nanomaterials (ENMs) based on open standards, ontologies and an interoperable design to enable a more effective, integrated approach to European research in nanotechnology. eNanoMapper supports the collaborative safety assessment for ENMs by creating a modular, extensible infrastructure for transparent data sharing, data analysis, and the creation of computational toxicology models for ENMs. eNanoMapper was funded by the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 604134. /system/content_providers/images/000/000/092/original/logo.png?1528313779
  • COG-Train

    COG-Train is an international educational initiative providing open-access learning in SARS-CoV-2...

    4 training materials
    COG-Train https://tess.elixir-europe.org/content_providers/cog-train COG-Train is an international educational initiative providing open-access learning in SARS-CoV-2 genomics. It aims to facilitate an increase in global genome sequencing and analysis capacity, reduce sequencing inequality and enhance pathogen surveillance. The programme’s training courses and development are built around our core concept of partnering with international researchers, public health experts and surveillance networks and providing open-access FREE training for all. COG-Train is funded by Wellcome Trust and the Foreign, Commonwealth & Development Office and led jointly by COVID-19 Genomics UK (COG-UK) consortium and Wellcome Connecting Science (WCS). Whole Viral Genome sequencing is an essential tool to identify and track the emergence and spread of SARS-CoV-2 variants as the COVID-19 pandemic progresses. Sequence data informs public health interventions and the further development of diagnostics, therapeutics and vaccines. There is inequity of access to pathogen sequencing worldwide, and COG-Train is committed to contributing towards efforts that close this gap. By building global partnerships with sequencing networks and scientists around the world, we hope to build a truly inclusive training programme that shares the many challenges faced in sequencing efforts, as well as highlighting the numerous success stories, and facilitating knowledge sharing. Outputs include a series of massive online, open-access courses on all aspects of SARS-CoV-2 sequencing based on WCS’s successful use of the FutureLearn platform, as well as week-long intensive virtual training courses, short expert workshops and concurrent distributed Classrooms, the latter of which utilises blended training. The distributed classroom model will be used to increase reach and impact of the learning materials, with training being delivered simultaneously in multiple classrooms across many countries. The training programme includes train-the-trainer components to help further build capacity in-country, rather than rely on a one-hit train and leave model. The COG-Train educational programme builds on the COG-UK values of data sharing, open collaboration, value for money, inclusivity and the prioritisation of public health impact. /system/content_providers/images/000/000/644/original/COG-Train_Logo.png?1657104279
  • EMBL-ABR

    EMBL Australia Bioinformatics Resource (EMBL-ABR) is a distributed national research...

    9 training materials
    0 upcoming events (193 past events)
    EMBL-ABR https://tess.elixir-europe.org/content_providers/embl-abr EMBL Australia Bioinformatics Resource (EMBL-ABR) is a distributed national research infrastructure providing bioinformatics support to life science researchers in Australia. EMBL-ABR aims to: 1. increase Australia’s capacity to collect, integrate, analyse, exploit, share and archive the large heterogeneous data sets now part of modern life sciences research 2. contribute to the development of and provide training in data, tools and platforms to enable Australia’s life science researchers to undertake research in the age of big data 3. showcase Australian research and datasets at an international level 4. enable engagement in international programs that create, deploy and develop best practice approaches to data management, software tools and methods, computational platforms and bioinformatics services. EMBL-ABR is structured as a hub/nodes model, with the Hub located at Melbourne Bioinformatics (formerly VLSCI), University of Melbourne. EMBL-ABR is also currently exploring engagement with the European infrastructure for biological information, ELIXIR, and other relevant international efforts. One of EMBL-ABR Key areas is TRAINING, and as such we are involved in diverse projects relevant for bioinformatics training in Australia, with a current focus on Open Science and Bioinformatics. /system/content_providers/images/000/000/072/original/embl-australia-logo-colour-FIN-e1462860151765.jpg?1488905402
  • INB: Spanish National Bioinformatics Institute

    The Spanish National Bioinformatics Institute (‘Instituto Nacional de Bioinformática’ in Spanish,...

    0 upcoming events (14 past events)
    INB: Spanish National Bioinformatics Institute https://tess.elixir-europe.org/content_providers/inb-spanish-national-bioinformatics-institute The Spanish National Bioinformatics Institute (‘Instituto Nacional de Bioinformática’ in Spanish, or short INB), founded in 2003 following the decentralized model of nodes of the Swiss Institute of Bioinformatics (SIB), is the bioinformatics technology platform of the Carlos III Health Institute (‘Instituto de Salud Carlos III‘ or ISCIII) since January 2018. The INB has increased the participant nodes to 19 research groups distributed across 13 institutions in Spain. The two main overarching objectives are maintaining and increasing the alignment of the INB with ELIXIR (European Life Science Infrastructure for Biological Information) looking for deeper synergies, while increasing the translational capacity of the INB towards the Spanish National Health System (SNS). The INB serves in the coordination, integration and development of Spanish bioinformatics resources in projects in the areas of genomics, proteomics and translational medicine. It has contributed to the creation of a consistent computational infrastructure in the area of bioinformatics, participated in national and international genome projects, and trained bioinformatics users and developers. The INB is in a strategic position as an interface between developments at the national and international level by research centers, initiatives such as the Global Alliance for Genomics and Health (GA4GH), and organizations such as ELIXIR, and bioinformatic groups directly related to clinical practice. **Spain is member of ELIXIR since 2015, with the INB as the Spanish national node**. Within ELIXIR, the INB is responsible for the bioinformatics infrastructure offered by Spain, and therefore, should guarantee its alignment to the strategic areas put forward by ELIXIR. /system/content_providers/images/000/000/110/original/logoINB.png?1550073283