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UPGMA Worked Example

A walkthrough of clustering 7 biological sequences (A-G) using the Unweighted Pair-Group Method with Arithmetic mean (UPGMA) method. Note that UPGMA is actually a generic method and thus the walkthrough could apply to any objects A-G for which pairwise distances can be calculated. A small CGI site for generating a UPGMA tree from a distance matrix can be found here. The source data for this worked example is a subset of Cytochrome C distances from Table 3 of one of the seminal phylogenetic papers: Fitch WM & Margoliash E (1967). Construction of phylogenetic trees. Science 155:279-84. PowerPoint timings are set up to be consistent with autolooping the presentation.

** Keywords: **Molecular phylogeny, Phylogenetics, Upgma

** Target audience: **Beginners

** Authors: **Richard Edwards

** Remote created date: **2014-08-04

** Remote updated date: **2017-10-09

UPGMA Worked Example
https://www.mygoblet.org/training-portal/materials/upgma-worked-example
https://tess.elixir-europe.org/materials/upgma-worked-example
A walkthrough of clustering 7 biological sequences (A-G) using the Unweighted Pair-Group Method with Arithmetic mean (UPGMA) method. Note that UPGMA is actually a generic method and thus the walkthrough could apply to any objects A-G for which pairwise distances can be calculated. A small CGI site for generating a UPGMA tree from a distance matrix can be found here. The source data for this worked example is a subset of Cytochrome C distances from Table 3 of one of the seminal phylogenetic papers: Fitch WM & Margoliash E (1967). Construction of phylogenetic trees. Science 155:279-84. PowerPoint timings are set up to be consistent with autolooping the presentation.
Richard Edwards
Molecular phylogeny, Phylogenetics, Upgma
Beginners
2014-08-04
2017-10-09