e-learning

Multi-sample batch correction with Harmony and SnapATAC2

Abstract

About This Material

This is a Hands-on Tutorial from the GTN which is usable either for individual self-study, or as a teaching material in a classroom.

Questions this will address

  • Why is batch correction important during the analysis of data from multiple samples?
  • How is batch correction performed on single cell ATAC-seq data?

Learning Objectives

  • Perform batch correction on a dataset collection of multiple single cell ATAC-seq samples.
  • Learn how Harmony and other batch correction algorithms remove batch effects.

Licence: Creative Commons Attribution 4.0 International

Keywords: 10x, Single Cell, epigenetics

Target audience: Students

Resource type: e-learning

Version: 1

Status: Active

Prerequisites:

  • Introduction to Galaxy Analyses
  • Pre-processing of 10X Single-Cell ATAC-seq Datasets
  • Single-cell ATAC-seq standard processing with SnapATAC2

Learning objectives:

  • Perform batch correction on a dataset collection of multiple single cell ATAC-seq samples.
  • Learn how Harmony and other batch correction algorithms remove batch effects.

Date modified: 2025-02-28

Date published: 2025-02-28

Authors: Timon Schlegel

Contributors: Diana Chiang Jurado, Saskia Hiltemann, Timon Schlegel


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