e-learning
Indexing and profiling microbes with MetaSBT
Abstract
Introduction
About This Material
This is a Hands-on Tutorial from the GTN which is usable either for individual self-study, or as a teaching material in a classroom.
Questions this will address
- What are Sequence Bloom Trees and how does MetaSBT use them for genomics?
- How do you build a custom viral database from a set of reference genomes?
- How can an existing MetaSBT database be updated with new viruses?
- How do you profile a query viral genome against a database to determine its identity and novelty?
- How can we interpret the viral genome profiling results?
Learning Objectives
- Understand the fundamental concepts of MetaSBT for efficient genomic indexing.
- Learn to use the
metasbt_index
tool to create a custom viral database. - Learn to use the
metasbt_index
tool to update an existing database. - Learn to use the
metasbt_profile
tool to identify and characterize a query viral genome. - Be able to interpret the similarity reports generated by the profiling tool.
Licence: Creative Commons Attribution 4.0 International
Keywords: Microbiome, diversity, metagenomics, taxonomic profiling
Target audience: Students
Resource type: e-learning
Version: 7
Status: Active
Prerequisites:
- Galaxy Basics for everyone
- Introduction to Galaxy Analyses
Learning objectives:
- Understand the fundamental concepts of MetaSBT for efficient genomic indexing.
- Learn to use the
metasbt_index
tool to create a custom viral database. - Learn to use the
metasbt_index
tool to update an existing database. - Learn to use the
metasbt_profile
tool to identify and characterize a query viral genome. - Be able to interpret the similarity reports generated by the profiling tool.
Date modified: 2025-08-25
Date published: 2025-08-25
Contributors: Daniel Blankenberg
Scientific topics: Metagenomics, Microbial ecology, Taxonomy
Activity log