e-learning

Genome Assembly of a bacterial genome (MRSA) sequenced using Illumina MiSeq Data

Abstract

Sequencing (determining of DNA/RNA nucleotide sequence) is used all over

About This Material

This is a Hands-on Tutorial from the GTN which is usable either for individual self-study, or as a teaching material in a classroom.

Questions this will address

  • How to check the quality of the MiSeq data?
  • How to perform an assembly of a bacterial genome with MiSeq data?
  • How to check the quality of an assembly?

Learning Objectives

  • Run tools to evaluate sequencing data on quality and quantity
  • Process the output of quality control tools
  • Improve the quality of sequencing data
  • Run a tool to assemble a bacterial genome using short reads
  • Run tools to assess the quality of an assembly
  • Understand the outputs of tools to assess the quality of an assembly

Licence: Creative Commons Attribution 4.0 International

Keywords: Assembly, assembly, illumina, microgalaxy

Target audience: Students

Resource type: e-learning

Version: 17

Status: Active

Prerequisites:

  • Introduction to Galaxy Analyses
  • Quality Control

Learning objectives:

  • Run tools to evaluate sequencing data on quality and quantity
  • Process the output of quality control tools
  • Improve the quality of sequencing data
  • Run a tool to assemble a bacterial genome using short reads
  • Run tools to assess the quality of an assembly
  • Understand the outputs of tools to assess the quality of an assembly

Date modified: 2025-11-18

Date published: 2021-03-24

Authors: Bazante Sanders, Bérénice Batut

Contributors: Anthony Bretaudeau, Bazante Sanders, Björn Grüning, Bérénice Batut, Cristóbal Gallardo, Deepti Varshney, Helena Rasche, Miaomiao Zhou, Nate Coraor, Paul Zierep, Saskia Hiltemann, Teresa Müller, Verena Moosmann, Wolfgang Maier, pimarin

Scientific topics: Sequence assembly, Whole genome sequencing, Public health and epidemiology, Genomics, Microbiology


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