hands-on tutorial
Evaluating and ranking a set of pathways based on multiple metrics
The questions this addresses are:
- How to evaluate a set of heterologous pathways ?
The objectives are:
- Calculate the production flux of the lycopene target molecule using Flux Balance Analysis tool.
- Compute thermodynamics values to optimize the yield of the reaction producing the lycopene using Thermo tool.
- Compute the global score for the previous annotated pathways.
- Rank the computed heterologous pathways depending on their score.
Licence: Creative Commons Attribution 4.0 International
Keywords: Synthetic Biology
Target audience: Students
Resource type: hands-on tutorial
Version: 7
Status: Active
Prerequisites:
Introduction to Galaxy Analyses
Learning objectives:
Calculate the production flux of the lycopene target molecule using Flux Balance Analysis tool.
- Compute thermodynamics values to optimize the yield of the reaction producing the lycopene using Thermo tool.
- Compute the global score for the previous annotated pathways.
- Rank the computed heterologous pathways depending on their score.
Date modified: 2024-06-14
Date published: 2022-09-26
Contributors: Guillaume Gricourt, Ioana Popescu, Jean-Loup Faulon, Joan Hérisson, Kenza Bazi-Kabbaj, Thomas Duigou
Scientific topics: Synthetic biology
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