hands-on tutorial

Evaluating and ranking a set of pathways based on multiple metrics

The questions this addresses are:
- How to evaluate a set of heterologous pathways ?

The objectives are:
- Calculate the production flux of the lycopene target molecule using Flux Balance Analysis tool.
- Compute thermodynamics values to optimize the yield of the reaction producing the lycopene using Thermo tool.
- Compute the global score for the previous annotated pathways.
- Rank the computed heterologous pathways depending on their score.

Licence: Creative Commons Attribution 4.0 International

Keywords: Synthetic Biology

Target audience: Students

Resource type: hands-on tutorial

Version: 7

Status: Active

Prerequisites:

Introduction to Galaxy Analyses

Learning objectives:

Calculate the production flux of the lycopene target molecule using Flux Balance Analysis tool.
- Compute thermodynamics values to optimize the yield of the reaction producing the lycopene using Thermo tool.
- Compute the global score for the previous annotated pathways.
- Rank the computed heterologous pathways depending on their score.

Date modified: 2024-06-14

Date published: 2022-09-26

Authors: Guillaume Gricourt, Ioana Popescu, Jean-Loup Faulon, Joan Hérisson, Kenza Bazi-Kabbaj, Thomas Duigou

Contributors: Guillaume Gricourt, Ioana Popescu, Jean-Loup Faulon, Joan Hérisson, Kenza Bazi-Kabbaj, Thomas Duigou

Scientific topics: Synthetic biology


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