Exploiting collisions between DNA molecules to characterize the genomic structures of complex communities

Meta3C is an experimental and computational approach that exploits the physical contacts experienced by DNA molecules sharing the same cellular compartments. These collisions provide a quantitativeinformation that allows interpreting and phasing the genomes present within complex mixes of species without prior knowledge. Not only the exploitation of chromosome physical 3D signatures hold interesting premises regarding solving the genome sequences from discrete species, but it also allows assigning mobile elements such as plasmids or phages to their hosts.

Keywords: metagenomics

Licence: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0

Remote created date: 2016-12-15

Remote updated date: 2017-01-11

Exploiting collisions between DNA molecules to characterize the genomic structures of complex communities https://tess.elixir-europe.org/materials/exploiting-collisions-between-dna-molecules-to-characterize-the-genomic-structures-of-complex-communities-e13ff1e3-f218-4367-b445-2a8e18bb7834 Meta3C is an experimental and computational approach that exploits the physical contacts experienced by DNA molecules sharing the same cellular compartments. These collisions provide a quantitativeinformation that allows interpreting and phasing the genomes present within complex mixes of species without prior knowledge. Not only the exploitation of chromosome physical 3D signatures hold interesting premises regarding solving the genome sequences from discrete species, but it also allows assigning mobile elements such as plasmids or phages to their hosts. metagenomics 2016-12-15 2017-01-11