e-learning

Deciphering Virus Populations - Single Nucleotide Variants (SNVs) and Specificities in Baculovirus Isolates

Abstract

Baculoviruses of the family Baculoviridae are among the most intensively

About This Material

This is a Hands-on Tutorial from the GTN which is usable either for individual self-study, or as a teaching material in a classroom.

Questions this will address

  • How can the genetic variability of a baculovirus isolate be analysed?
  • How can single nucleotide variants (SNVs) be identified across multiple isolates?
  • How can SNVs be used as markers to analyse the composition of baculovirus isolates?

Learning Objectives

  • Understand the significance of SNVs.
  • Determine variable SNV positions for multiple isolates using a common reference genome.
  • Transform the output (VCF file) to a readable table format.
  • Interpret the SNV data to analyse the intra-isolate variability of baculoviruses.

Licence: Creative Commons Attribution 4.0 International

Keywords: Variant Analysis

Target audience: Students

Resource type: e-learning

Version: 1

Status: Active

Prerequisites:

  • Introduction to Galaxy Analyses
  • Mapping
  • Quality Control

Learning objectives:

  • Understand the significance of SNVs.
  • Determine variable SNV positions for multiple isolates using a common reference genome.
  • Transform the output (VCF file) to a readable table format.
  • Interpret the SNV data to analyse the intra-isolate variability of baculoviruses.

Date modified: 2025-02-24

Date published: 2025-02-24

Authors: Jörg Wennmann

Contributors: Björn Grüning, Jörg Wennmann, Wolfgang Maier

Scientific topics: Genetic variation


Activity log