ELIXIR Structural Bioinformatics 3: Predicting the effect of mutation on protein function

This workflow builds on the previous training workflows in this series on building protein models and identifying functional domains or ligand binding sites - and introduces methods to predict how mutations can impact on protein function.

It is designed to lead you through the process of finding sequence or structure information for your protein of interest, and using it as a search query to investigate several different online tools - each able to provide information about different mutation effects.

It will help guide you through exploring these tools and interpreting the predicted effect information to give you greater understanding of how variability in your protein may impact on function.

Keywords: Sequence analysis, Functional Annotation, Functional analysis