Whole Genome Sequencing: Decoding the Language of Life and Health

Whole genome sequencing is a relatively new technology that allows us to ‘read’ a person’s or organism’s entire genetic code. But how does it work and what does it mean for all of us? How do scientists and clinicians begin to make sense of the vast amount of information that whole genome sequencing provides? And how will this new sequencing technology be used for the benefit of patients in the new NHS Genomic Medicine Service in England?
Topics covered:
- The composition, structure and function of a genome.
- The process and the importance of DNA replication.
- Genomic variation and its connections with health and disease.
- The evolution of genome sequencing.
- The advent and the possibilities of next generation sequencing.
- The preparation and processing of DNA samples in whole genome sequencing.
- The interpretation of genomic information for clinicians and patients.
- The limitations and challenges faced by current sequencing technologies.
- Additional, incidental and secondary findings from whole genome sequencing.
- The ownership, storing and sharing of genomic data.
- The impact of whole genome sequencing on healthcare in the future

Scientific topics: Rare diseases

Keywords: Rare Diseases & Research

Resource type: e-learning

Target audience: Health Care Professionals, health professionals, medical students, science students

Difficulty level: Advanced

Whole Genome Sequencing: Decoding the Language of Life and Health https://tess.elixir-europe.org/materials/whole-genome-sequencing-decoding-the-language-of-life-and-health This course is available on FutureLearn and developed by Health Education England (NHS). The course has been designed for healthcare professionals and science/medical students who have limited or no understanding of the who genome sequencing process and its many varied uses. Non-specialists who want to learn more about sequencing and genomic medicine are also very welcome. Rare diseases Rare Diseases & Research Health Care Professionals health professionals medical students science students