Introduction to Sample Size Calculation

  1. Introduction

  2. Sample Size Calculation – Basic Formula

  3. Example 1

  4. Calculating In Terms of ‘Difference to Detect’ & Power From Sample Size

  5. Example 2

  6. Different Numbers Per Group

  7. Different Variances for Groups

  8. Binary Data

  9. Allowing for Drop-outs

  10. Demonstrating Equivalence

  11. More Complex Designs

Keywords: Sample size, Roslin Institute

Difficulty level: Beginner

Licence: Other (Not Open)

Authors: Helen Brown

Introduction to Sample Size Calculation https://tess.elixir-europe.org/materials/introduction-to-sample-size-calculation Training session with Dr Helen Brown, Senior Statistician, at The Roslin Institute, January 2016. These training sessions were given to staff and research students at the Roslin Institute. The material is also used for the Animal Biosciences MSc course taught at the Institute. A spreadsheet to carry out the calculations described in the presentation may be copied here: http://datashare.is.ed.ac.uk/handle/10283/1996 Sample size, Roslin Institute