Genomic Technologies in Clinical Diagnostics: Molecular Techniques

This postgraduate-level course, in combination with Genomic Technologies in Clinical Diagnostics: Next Generation Sequencing Technologies, will help you understand these new and established genetic technologies, and their application to clinical practice.
This course focuses on molecular techniques. By the end, you will be able to demonstrate knowledge and applicability of the molecular principles behind:
• array comparative genomic hybridisation (array CGH);
• karyotyping;
• fluorescent in situ hybridisation (FISH);
• Southern blotting;
• multiplex ligation probe amplification (MLPA);
• polymerase chain reaction (PCR) and Sanger sequencing;
• quantitative fluorescent PCR (QF-PCR);
• single nucleotide polymorphism (SNP) genotyping and genome wide association studies (GWAS);
• and the extraction and analysis of cell free fetal DNA, including non-invasive prenatal testing (NIPT).

Keywords: Rare Diseases & Research

Difficulty level: Advanced

Genomic Technologies in Clinical Diagnostics: Molecular Techniques https://tess.elixir-europe.org/materials/genomic-technologies-in-clinical-diagnostics-molecular-techniques Online courses from St George’s, University of London on molecular techniques (3 weeks / 5 hours per weekly study). Rare Diseases & Research