Genomic Technologies in Clinical Diagnostics: Molecular Techniques

This course focuses on molecular techniques. By the end, you will be able to demonstrate knowledge and applicability of the molecular principles behind:
- array comparative genomic hybridisation (array CGH);
- karyotyping;
- fluorescent in situ hybridisation (FISH);
- Southern blotting;
- multiplex ligation probe amplification (MLPA);
- polymerase chain reaction (PCR) and Sanger sequencing;
- quantitative fluorescent PCR (QF-PCR);
- single nucleotide polymorphism (SNP) genotyping and genome wide association studies (GWAS);
- and the extraction and analysis of cell free fetal DNA, including non-invasive prenatal testing (NIPT).

Scientific topics: Rare diseases

Keywords: Rare Diseases & Research

Resource type: e-learning

Target audience: Scientists, healthcare professionals

Difficulty level: Advanced

Genomic Technologies in Clinical Diagnostics: Molecular Techniques https://tess.elixir-europe.org/materials/genomic-technologies-in-clinical-diagnostics-molecular-techniques This course is available on FutureLearn and developed by St George’s, University of London. This postgraduate-level course, in combination with Genomic Technologies in Clinical Diagnostics: Next Generation Sequencing Technologies, will help you understand these new and established genetic technologies, and their application to clinical practice. This course focuses on molecular techniques. Rare diseases Rare Diseases & Research Scientists healthcare professionals