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2 events found

Organizer: University of Cambridge 

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Target audience: cellular models of disease ... 

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City: Bogota  or Cambridge 

  • Mining gene-disease associations and drug target validation with Open Targets

    17 October 2016

    Cambridge, United Kingdom

    Elixir node event
    Mining gene-disease associations and drug target validation with Open Targets https://tess.elixir-europe.org/events/mining-gene-disease-associations-and-drug-target-validation-with-open-targets [Open Targets](https://www.opentargets.org/) was founded by three global leading institutions in the fields of pharmaceuticals, bioinformatics and genomics, GSK, EMBL-EBI, the Wellcome Trust Sanger Institute, and recently joined by Biogen, the world’s oldest independent biotechnology company. We combine large-scale genomic experiments with objective statistical and computational techniques to identify and validate the causal links between targets, pathways and diseases. Cross-cutting several therapeutic areas, we generate cellular models of disease through gene editing technologies or single cell analysis. In addition to clinical samples, iPS cells and cellular organoids are resourced to provide cellular phenotyping with high physiological relevance. Open Targets integrates comprehensive datasets from a myriad of renowned public databases, such as UniProt, ChEMBL, Ensembl, NHGRI-EBI GWAS, EuropePMC, COSMIC, GTEx, among others. The data and analytical processes are developed by a set of interlinking projects. The purpose of this half-day workshop is to acquaint participants with the Open Targets project and its Target Validation interface and introduce the tools for visualisation and interpretation of gene-disease associations and target validation based on a comprehensive platform with data from various publicly available databases. By the end of this half-day workshop, users will be able to carry out effective searches of data, use the web application to visualise genes, variants, ontology, pathways (and more) in the context of human disease and therapeutics. Please note that if you are not eligible for a University of Cambridge [Raven](http://www.ucs.cam.ac.uk/docs/faq/raven/n5) account you will need to Book or register Interest by linking [here](http://bioinfotraining.bio.cam.ac.uk/booking-form/?event-id=1830221&course-title=OpenTargets%20workshop).'' 2016-10-17 12:00:00 UTC 2016-10-17 16:00:00 UTC University of Cambridge Craik-Marshall Building, Cambridge, United Kingdom Craik-Marshall Building Cambridge United Kingdom CB2 3AR University of Cambridge Bioinformatics Training [] This course is suitable for all users who have an interest in biomedical research and therapeutics with a special emphasis on drug discovery and target validation. It is also useful to those who seek to find out how large-scale genomic experimentscellular models of disease and computational techniques are used to identify and validate the causal links between targetspathways and diseases.Graduate studentsPostdocs and Staff members from the University of CambridgeInstitutions and other external Institutions or individuals workshops_and_courses [] HDRUK
  • Open Targets: Integrating genetics and genomics for disease biology and translational medicine

    17 October 2019

    Cambridge, United Kingdom

    Elixir node event
    Open Targets: Integrating genetics and genomics for disease biology and translational medicine https://tess.elixir-europe.org/events/open-targets-integrating-genetics-and-genomics-for-disease-biology-and-translational-medicine Open Targets is a public-private partnership to use human genetics, genomic data and drug information for systematic identification and prioritisation of therapeutic targets. This module introduces the Open Targets partnership, its underlying projects and the bioinformatics resources for researchers studying associations of human genes with diseases. We offer interactive and hands-on experience with Open Targets Platform and Open Targets Genetics, open source tools of integrated biological and chemical data for drug target identification and prioritisation. We cover user cases relevant to the biomedical and pharmaceutical communities and can customise the course according to specific therapeutic areas. The training room is located on the first floor and there is currently no wheelchair or level access available to this level. Please note that if you are not eligible for a University of Cambridge [Raven](http://www.ucs.cam.ac.uk/docs/faq/raven/n5) account you will need to book or register your interest by linking [here](http://bioinfotraining.bio.cam.ac.uk/booking-form/?event-id=3093271&course-title=OpenTargets%20workshop).'' 2019-10-17 12:00:00 UTC 2019-10-17 16:00:00 UTC University of Cambridge Craik-Marshall Building, Cambridge, United Kingdom Craik-Marshall Building Cambridge United Kingdom CB2 3AR Pharmacogenomics Genotype and phenotype Data visualisation Bioinformatics University of Cambridge Bioinformatics Training [] This course is suitable for anyone who has an interest in biomedical research and therapeutics with a special emphasis on drug discovery and target validation. It is also useful to those who wish to find out how large-scale genomic experimentscellular models of disease and computational techniques are used to identify and validate the causal links between targetspathways and diseases.Graduate studentsPostdocs and Staff members from the University of CambridgeInstitutions and other external Institutions or individuals workshops_and_courses [] HDRUK
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