Educators:
Aleksandr Zlobin, Max Beining, Christina Wüst, Sevilay Gulesen, Sophie Maclure, Paul Kluge, Hannes Junker (RBC)

Date:
17-21 August 2026

Location:
Scads.AI headquarters, Leipzig

Content:
We offer theoretical introduction into modern approaches of computational protein and drug design, followed by practical hands-on sessions. Technologies covered include

• Rosetta and pyRosetta
• AlphaFold, Boltz, OpenFold, RosettaFold3
• ProteinMPNN, LigandMPNN
• RFdiffusion
• BindCraft

We will discuss their value and application scenarios in designing

• Therapeutic peptides
• Vaccines
• Enzymes
• And other therapeutic modalities

The workshop is open for students and researchers at any career level and is free of charge. The working language of the event is English.

In 2026, we offer a significantly enriched program with a particular focus on the freshest RosettaCommons technologies. Additionally, the workshop will feature a hackathon-style project session to immediately try out the learned tools.

Learning goals:
Understand the space of available protein and drug design technologies, their application scenarios, requirements and limitations. Get experience in applying these tools to model problems. Understand practical considerations of designing proteins and drugs with particular function and therapeutic modality. Learn how to apply computational design tools in your own project.

Prerequisites:
Basic knowledge of Python, Bash.

Keywords:
Protein design, enzyme design, drug discovery, structure prediction, AlphaFold, ProteinMPNN, Rfdiffusion, Rosetta

Tools:
Google Colab, ColabFold, AlphaFold, OpenFold, PyMol, Rosetta, pyRosetta, ProteinMPNN, Rfdiffusion, BindCraft