Educators:
Robert Heyer, Alexander Sczyrba, Kay Schallert, Emanuel Lang (BiGi)

Date
30.09.2024

Location:
GCB Bielefeld

Contents:
Understanding the taxonomic and functional makeup of microbiomes and their activity is crucial for comprehending various diseases like inflammatory bowel disease, environmental processes such as soil dynamics, and biotechnological applications like biogas production. This understanding can be achieved through the analysis of microbial genes (metagenomics), transcripts (metatranscriptomics), proteins (metaproteomics), or metabolites (metabolomics). Researchers, in addition to experimental expertise, require bioinformatics skills to analyze and integrate data pertaining to these microbial features.This workshop aims to illustrate a combined bioinformatics workflow for whole-genome sequencing [1] and metaproteomics analysis [2,3] using a microbiome as an example. Additionally, we will demonstrate how to map omics features to metabolomics pathways using the MPAPathwayTool [4] and conduct flux balance analysis.

Learning goals:
Understanding data analysis for metagenomics and metaproteomics

Prerequisites:
Nothing

Keywords:
Metaproteomics, Metagenomics, Microbiome

Tools:
MetaProteomeAnalyzer, MPAPathwayTool