An introduction to long-read sequencing
Organizer: University of Cambridge
Host institution: University of Cambridge Bioinformatics Training
Start: Thursday, 13 February 2020 @ 09:30
End: Friday, 14 February 2020 @ 17:00
Venue: Craik-Marshall Building
Country: United Kingdom
Postcode: CB2 3AR
Scientific topic: Biology, BioinformaticsTarget audience:
- This is aimed for life scientists with little or no experience in long-read sequencing that are looking at implementing these approaches in their research.
- Graduate students
- Postdocs and Staff members from the University of Cambridge
- Institutions and other external Institutions or individuals
Analysis of whole genome data unearths a multitude of variants of different classes, which need to be filtered, annotated and validated to arrive at a causative variant for a disease. The current short length sequences, whilst being excellent at identifying single nucleotide variants and short insertions/deletions, struggle to correctly map structural variants (SVs). Long-read sequencing technologies offer improvements in the characterisation of genetic variation and regions that are difficult to assess with short-read sequences.
The aim of this course is to familiarise participants with long read sequencing technologies, their applications and the bioinformatics tools used to assemble this kind of data. Lectures will introduce this technology and provide insight into methods for the analysis of genomic data, while the hands-on sessions will allow participants to run analysis pipelines, focusing on data generated by the Oxford Nanopore Technologies (ONT) platform.
The training room is located on the first floor and there is currently no wheelchair or level access available to this level.
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