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4 events found

Keywords: service descriptions  or Open Targets  or Python  or Metabolism 

  • Open Targets Workshop

    28 March 2019

    EMBL-EBI

    Open Targets Workshop https://tess.elixir-europe.org/events/open-targets-workshop-55d54e1b-0a19-4e14-9719-6df0ad7054b9 In this workshop, we introduce Open Targets and its underlying projects for data integration for access and visualisation of biological data in drug target identification and discovery. 2019-03-28 09:00:00 UTC 2019-03-28 00:00:00 UTC EMBL-EBI, EMBL-EBI EMBL-EBI EMBL-EBI [] [] [] workshops_and_courses [] Open Targets
  • Regulatory Oxylipins

    1 - 4 April 2019

    Gent, Belgium

    Elixir node event
    Regulatory Oxylipins https://tess.elixir-europe.org/events/regulatory-oxylipins-661da9dc-2159-4a34-8809-7851dfbe0b8a Oxylipins, from plants and other organisms, form a constantly growing group of signalling molecules that comprise oxygenated fatty acids and their metabolites. The most renowned regulatory oxylipins are undoubtedly the jasmonates, which, following their discovery in the 1960s, became recognized as regulators of defence, floral organ development and fertility, as growth inhibitors and modulators of senescence, and as elicitors of specialized metabolism in numerous plant species. As such, the jasmonates currently belong to an elite group of heavily investigated phytohormones. Over the last decade, the understanding of biosynthesis, metabolism, and action of regulatory oxylipins has greatly advanced. The ROXY2019 meeting wishes to bring together the international community and leading researchers in the field. Thereby it aims to provide a timely and exciting forum to present and discuss the recent advances and expertise on the study of these molecules that are so crucial for plant growth, development, metabolism, and interaction with the environment. There will be seven plenary sessions that, through combining lectures from invited speakers and short talks on selected abstracts and posters, will highlight the various aspects involved in Regulatory Oxylipin research. These sessions cover the following major themes: Regulatory oxylipins in emerging model systems and non-plant systems, Biochemistry and structural biology, Control of growth and defence, Control of Metabolism, Reproduction, Jasmonate signalling mechanisms and Long-distance signalling, Ecology. We look forward to your contributions to make this an exciting conference. See you in Gent! The organizers Alain Goossens and Ted Farmer Poster information Format: A0 (841 x 1189 mm / 33.1 x 46.8 in), portrait orientation 2019-04-01 09:00:00 UTC 2019-04-04 17:00:00 UTC VIB Conferences - Alain Goossens & Ted Farmer Ghent University - Aula, 9, Voldersstraat, Gent, Belgium Ghent University - Aula, 9, Voldersstraat Gent Oost-Vlaanderen Belgium 9000 [] conferences@vib.be Faculty of ScienceJournal of Experimental BotanyPCP (Plant & Cell Physiology)The Plant CellThe Plant Journal [] [] [] Regulatory OxylipinsBiochemistrystructural biologyMetabolismreproductionJasmonate signallingEcology
  • Open Targets webinar - Bristol-Myers Squibb

    12 April 2019

    Open Targets webinar - Bristol-Myers Squibb https://tess.elixir-europe.org/events/open-targets-webinar-c-comend-training-in-translational-research In this webinar, we introduce Open Targets and its bioinformatics tools, namely Open Targets Platform and Open Targets Genetics, comprehensive and robust data integration resources for systematic target identification and prioritisation in drug discovery. 2019-04-12 09:00:00 UTC 2019-04-12 00:00:00 UTC [] [] [] workshops_and_courses [] Open Targets
  • Open Targets Genetics at ESHG

    15 June 2019

    Sweden

    Open Targets Genetics at ESHG https://tess.elixir-europe.org/events/workshop-at-eshg In this workshop, we will introduce Open Targets Genetics Portal as part of the Open Targets ecosystem, highlighting variant-centric statistical evidence for prioritizing candidate causal variants at trait-associated loci, and identifying potential drug targets. We will present POSTGAP, a pipeline which merges genetic associations curated from literature with functional genomics, epigenetic and expression data (e.g., eQTL, promoter capture Hi-C, DNase hypersensitivity sites, regulatory elements) to resolve association signals at a locus and link each variant to its target gene(s) using a single evidence score. The portal also incorporates pre-computed fine-mapping at trait-associated loci across hundreds of UK Biobank phenotypes as well as cross-trait colocalization, furthering drug repurposing opportunities. This workshop will enable you to effectively use Open Targets Genetics to gain biological insight, prioritize genes, and inform target decision-making. Intended Audience: Attendees interested in the translational application of genetics and genomics with an emphasis on the identification of target genes of trait-associated loci, drug target identification, prioritisation and repurposing. Participants should bring their laptops for exploration of the Open Targets Genetics Portal in situ. 2019-06-15 09:00:00 UTC 2019-06-15 00:00:00 UTC Gothenburg, Sweden Gothenburg Sweden [] [] [] workshops_and_courses [] Open Targets
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