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Keywords: service descriptions  or Open Targets  or Allergy 

  • Type 2 Immunity in Homeostasis and Disease

    21 - 22 February 2019

    Brugge, Belgium

    Type 2 Immunity in Homeostasis and Disease https://tess.elixir-europe.org/events/type-2-immunity-in-homeostasis-and-disease Type 2 inflammation rich in eosinophils, basophils and mast cells and orchestrated by Th2 lymphocytes has been mainly studied in the context of allergies and immune responses to helminths. Since the discovery of type 2 innate lymphoid cells there has been a strong interest in understanding how type 2 immunity is induced and regulated, for example by barrier epithelial cells. Given the recent introduction of new biologics that target type 2 cytokines to treat severe allergic disease, we are accumulating a lot of new insights on type 2 immune responses in humans as well. This meeting will not only focus on new effector and regulatory mechanisms of the type 2 immune response. It will also offer a number of talks taking a broader look on type 2 immunity, dealing with such topics as type 2 immunity in homeostasis, growth and repair, metabolism, neuro-immune interactions and cancer. Understanding these alternative roles for type 2 immunity will be important to address the benefits and potential pitfalls of long-term inhibition of type 2 immunity by biologicals and could elucidate new therapeutic pathways for very common diseases like asthma, obesity, diabetes and cancer. Abstracts can be submitted for the following topics: Tissue homeostasis and repair Type 2 Neuro-immune axis Type 2 in allergy, asthma & helminth infection Type 2 Immunity & Cancer Deadlines: • Early Bird: 10 January 2019 • Late Registration: 7 February 2019 • Abstract deadline: 19 December 2018 2019-02-21 08:00:00 UTC 2019-02-22 18:00:00 UTC VIB Conferences OLD ST. JOHN SITE, Zonnekemeers, Brugge, Belgium OLD ST. JOHN SITE, Zonnekemeers Brugge West-Vlaanderen Belgium 8000 VIBGhent UniversityCell Press confferences@vib.be Vector Builder [] meetings_and_conferences [] ImmunityCancer, Cancer Biomarkers, Cancer Biomarkers in Clinical Use, Types of Biomarker and Biomarkers, Surgical oncology, Pediatric Oncology, Haematologist-oncology, Gynecologist oncology, Orthopaedic Oncology, Breast Cancer, Neuro-oncology, Pathophysiology of Cancer, Cancer Pharmacology, Cancer Therapeutics, Homeopathy Cancer Treatment Cancer Epigenetics, Cancer: Lifestyle and Nutrition, Cancer Prognosis and Predictive Factor, Cancer Proteomics, Molecular Epidemiology of Cancer, Cancer Nursing and Care, Cancer Diagnosis, Cancer Biopsy, Magnetic Resonance Imaging (MRI),Factors Associated with Cancer Prevalence, Cancer Pharma Industry, Economic Impact on CancerAllergyAsthmaType 2 immunity
  • Workshop at ESHG

    15 June 2019

    Sweden

    Workshop at ESHG https://tess.elixir-europe.org/events/workshop-at-eshg In this workshop, we will introduce Open Targets Genetics Portal as part of the Open Targets ecosystem, highlighting variant-centric statistical evidence for prioritizing candidate causal variants at trait-associated loci, and identifying potential drug targets. We will present POSTGAP, a pipeline which merges genetic associations curated from literature with functional genomics, epigenetic and expression data (e.g., eQTL, promoter capture Hi-C, DNase hypersensitivity sites, regulatory elements) to resolve association signals at a locus and link each variant to its target gene(s) using a single evidence score. The portal also incorporates pre-computed fine-mapping at trait-associated loci across hundreds of UK Biobank phenotypes as well as cross-trait colocalization, furthering drug repurposing opportunities. This workshop will enable you to effectively use Open Targets Genetics to gain biological insight, prioritize genes, and inform target decision-making. Intended Audience: Attendees interested in the translational application of genetics and genomics with an emphasis on the identification of target genes of trait-associated loci, drug target identification, prioritisation and repurposing. Participants should bring their laptops for exploration of the Open Targets Genetics Portal in situ. 2019-06-15 09:00:00 UTC 2019-06-15 00:00:00 UTC Gothenburg, Sweden Gothenburg Sweden [] [] [] workshops_and_courses [] Open Targets
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