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  • Disorder in Disorders: Pathogenic mechanisms of Intrinsically Disordered Proteins

    27 - 31 January 2020

    Disorder in Disorders: Pathogenic mechanisms of Intrinsically Disordered Proteins https://tess.elixir-europe.org/events/disorder-in-disorders-pathogenic-mechanisms-of-intrinsically-disordered-proteins Intrinsically Disordered Proteins (IDPs) are a highly abundant class of proteins that lack stable tertiary and/or secondary structures under physiological conditions. Numerous IDPs are associated with human diseases, including cancer, cardiovascular disease, amyloidoses, neurodegenerative diseases, and diabetes. Overall, intriguing interconnections among intrinsic disorder, cell signaling, and human diseases suggest that protein conformational diseases may result not only from protein misfolding, but also from misidentification, missignaling, and unnatural or nonnative folding. The winter school will alternate lectures to practicals. During lectures, experts of the field will provide students an overview of IDP biological mechanisms that develop pathogenic phenotypes. They will explore the concepts of folding, unfolding and misfolding, highlighting their differences and similarities. Practical exercises aim at transferring to students basic skills for the study of IDPs and will revolve around the use of bioinformatic tools to solve complex problems. The school includes a half-day workshop on ELIXIR interoperability services and support for the IDP Community. 2020-01-27 09:00:00 UTC 2020-01-31 17:00:00 UTC Università degli Studi di Padova - Casa della Gioventù, Via Rio Bianco,12 Università degli Studi di Padova - Casa della Gioventù, Via Rio Bianco,12 Protein properties Protein disordered structure Bioinformatics University of Padova, Italy idpfun@ngp-net.bio.unipd.it [] PhD studentspostdoctoral researchersLife Science Researchers workshops_and_courses first_come_first_servedregistration_of_interest intrinsically disordered proteinsprotein foldingbioinformatics
  • Health-RI Conference 2020

    30 January 2020

    Utrecht, Netherlands

    Health-RI Conference 2020 https://tess.elixir-europe.org/events/health-ri-conference-2020 At this year's Health-RI conference, leading experts will highlight how data is helping us to remain healthy, and how it can drive us towards a healthy future. We all want to stay healthy for as long as possible. How do we keep people healthy? When we do get ill, we look for the best treatment - the right treatment at the right time, tailor made. How can we learn from today's patients so that tomorrow's patients get better treatment? It's a matter of continuous learning and improvement - evidence based with the help of enormous amounts of data in different formats and from various sources. We're already learning how to combine that data in clever ways, tailoring it to specific situations and applying it to our everyday health choices. 2020-01-30 09:00:00 UTC 2020-01-30 17:00:00 UTC Health-RI Jaarbeurs Supernova, Utrecht, Utrecht, Netherlands Jaarbeurs Supernova, Utrecht Utrecht Utrecht Netherlands [] [] [] meetings_and_conferences [] FAIRHealthcarepersonalized medicinepersonal health trainArtificial Intelligence
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