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  • R for data science

    31 March - 3 April 2020

    Liverpool, United Kingdom

    R for data science https://tess.elixir-europe.org/events/r-for-data-science The course covered content for these learning objectives: To write your own custom functions To use for loops, apply functions and if statements To analyse large matrices of data in a semi-automated way To normalise data To quantify and correct batch effect To undertake the most common clustering algorithms including k-means and hierarchical To perform variable selection and present these results in different plots including heatmaps To do 2-way ANOVA To undertake multivariate modelling A brief introduction to machine learning. The course included brief theoretical introductions followed by hands on exercises based on real life research examples. 2020-03-31 09:00:00 UTC 2020-04-03 17:00:00 UTC Computational Biology Facility University of Liverpool, Liverpool, United Kingdom University of Liverpool Liverpool Merseyside United Kingdom L69 3GH Statistics and probability Bioinformatics University of Liverpool Computational Biology Facility (cbf@liverpool.ac.uk) [] [] 20 workshops_and_courses registration_of_interest R ProgrammingStatistical-model Statistics Pre-processingTranscriptomicsMetabolomicsProteomics
  • Bioinformatics for Precision Medicine: From Reads to Disease Variants. A GATK Workshop

    20 - 24 April 2020

    L'Hospitalet de Llobregat, Spain

    Elixir node event
    Bioinformatics for Precision Medicine: From Reads to Disease Variants. A GATK Workshop https://tess.elixir-europe.org/events/bioinformatics-for-precision-medicine-from-reads-to-disease-variants-a-gatk-workshop This 5-day course, with instructors from the Broad Institute (Boston, USA), covers all the steps from raw sequencing data to the obtention of lists of variants using the popular GATK4 software. The 4-day GATK workshop is followed by a last day covering topics on germline and somatic disease variant prioritization instructed by experts from the Unit of Bioinformatics for Precision Oncology (Catalan Institute of Oncology) and the Clinical Bioinformatics Area (Fundación Progreso y Salud). GATK workshops are designed to provide a comprehensive onboarding experience to new users, as well as access to more advanced understanding for users who are already familiar with the toolkit. 2020-04-20 09:30:00 UTC 2020-04-24 16:30:00 UTC Catalan Institute of Oncology (ICO), Broad Institute, Bellvitge Biomedical Research Institute (IDIBELL), Fundación Progreso y Salud (FPS) and Spanish National Bioinformatics Institute (INB/ELIXIR-ES) Institut Català d'Oncologia - L'Hospitalet de Llobregat, 203, Avinguda de la Granvia de l’Hospitalet, L'Hospitalet de Llobregat, Spain Institut Català d'Oncologia - L'Hospitalet de Llobregat, 203, Avinguda de la Granvia de l’Hospitalet L'Hospitalet de Llobregat Barcelona Spain Catalan Institute of Oncology (ICO) [] mixed audienceGATK newbiesGATK expertsGATK usersvariant discovery newbies 40 workshops_and_courses first_come_first_served GATKVariant detectionVariant callingVariant discoverydisease variantpriorizationgenomicsoncology
  • EMBO practical course on Integrative Modelling of Biomolecular Interactions

    11 - 15 May 2020

    Izmir, Turkey

    EMBO practical course on Integrative Modelling of Biomolecular Interactions https://tess.elixir-europe.org/events/embo-practical-course-on-integrative-modelling-of-biomolecular-interactions Proteins and their interactions are the mainstays of any cellular process. Studying these interactions at atomic detail is invaluable, paving the route to a mechanistic understanding of biological function and providing the first essential step towards the development of new drugs. Because of the costs and challenges associated with experimental techniques, structural biologists often turn to computational methods. This course will present docking-based computational methods and related bioinformatics approaches, aiming at predicting how proteins interact with other biomolecules or ligands. Lectures will provide the theoretical background on state-of-the-art algorithms for sampling and scoring docking models, describe the use of low- and high-resolution information, and conservation- and coevolution-based interface prediction methods. Further, to broaden the scope of the course beyond protein-protein interactions, we will cover protein-peptide docking, data-driven molecular simulations, and other relevant topics in the field, including modeling of large assemblies and membrane proteins. Roughly half of the course wil consist of practical sessions where the students will run computations on interesting biological problems. Finally, to encourage interaction between all participants and stimulate discussions, students will be prompted to present their own research, both in flash presentations and poster sessions, and bring their own research problems to dedicated troubleshooting sessions. 2020-05-11 09:00:00 UTC 2020-05-15 18:00:00 UTC Alexandre Bonvin, Ezgi Karaca and João Rodrigues Izmir Biomedicine and Genome Center Dokuz Eylül University Health Campus Mithatpasa St. 58/5 35340 Balcova, Izmir/TURKEY, Izmir, Turkey Izmir Biomedicine and Genome Center Dokuz Eylül University Health Campus Mithatpasa St. 58/5 35340 Balcova, Izmir/TURKEY Izmir Balçova Turkey 35340 [] embo2020.intmod@gmail.com BrukerF1000 ResearchBioExcelEMBO Press [] 24 workshops_and_courses [] Protein-Protein Complex modelingmodellingDockingInteractions

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