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3 events found

Keywords: Open Targets  or Genome Mapping  or Immunity 

  • Open Targets webinar - Daiichi-Sankyo

    15 May 2019

    United Kingdom

    Open Targets webinar - Daiichi-Sankyo https://tess.elixir-europe.org/events/open-targets-webinar-c-comend-training-in-translational-research In this webinar, we introduce Open Targets and its bioinformatics tools, namely Open Targets Platform and Open Targets Genetics, comprehensive and robust data integration resources for systematic target identification and prioritisation in drug discovery. 2019-05-15 09:00:00 UTC 2019-05-15 00:00:00 UTC Hinxton, United Kingdom Hinxton United Kingdom [] [] [] workshops_and_courses [] Open Targets
  • Open Targets Genetics at ESHG

    15 June 2019

    Sweden

    Open Targets Genetics at ESHG https://tess.elixir-europe.org/events/workshop-at-eshg In this workshop, we will introduce Open Targets Genetics Portal as part of the Open Targets ecosystem, highlighting variant-centric statistical evidence for prioritizing candidate causal variants at trait-associated loci, and identifying potential drug targets. We will present POSTGAP, a pipeline which merges genetic associations curated from literature with functional genomics, epigenetic and expression data (e.g., eQTL, promoter capture Hi-C, DNase hypersensitivity sites, regulatory elements) to resolve association signals at a locus and link each variant to its target gene(s) using a single evidence score. The portal also incorporates pre-computed fine-mapping at trait-associated loci across hundreds of UK Biobank phenotypes as well as cross-trait colocalization, furthering drug repurposing opportunities. This workshop will enable you to effectively use Open Targets Genetics to gain biological insight, prioritize genes, and inform target decision-making. Intended Audience: Attendees interested in the translational application of genetics and genomics with an emphasis on the identification of target genes of trait-associated loci, drug target identification, prioritisation and repurposing. Participants should bring their laptops for exploration of the Open Targets Genetics Portal in situ. 2019-06-15 09:00:00 UTC 2019-06-15 00:00:00 UTC Gothenburg, Sweden Gothenburg Sweden [] [] [] workshops_and_courses [] Open Targets
  • Open Targets Genetics at ESHG

    15 June 2019

    Sweden

    Open Targets Genetics at ESHG https://tess.elixir-europe.org/events/open-targets-genetics-at-eshg In this workshop, we will introduce Open Targets Genetics Portal as part of the Open Targets ecosystem, highlighting variant-centric statistical evidence for prioritizing candidate causal variants at trait-associated loci, and identifying potential drug targets. We will present POSTGAP, a pipeline which merges genetic associations curated from literature with functional genomics, epigenetic and expression data (e.g., eQTL, promoter capture Hi-C, DNase hypersensitivity sites, regulatory elements) to resolve association signals at a locus and link each variant to its target gene(s) using a single evidence score. The portal also incorporates pre-computed fine-mapping at trait-associated loci across hundreds of UK Biobank phenotypes as well as cross-trait colocalization, furthering drug repurposing opportunities. This workshop will enable you to effectively use Open Targets Genetics to gain biological insight, prioritize genes, and inform target decision-making. Intended Audience: Attendees interested in the translational application of genetics and genomics with an emphasis on the identification of target genes of trait-associated loci, drug target identification, prioritisation and repurposing. Participants should bring their laptops for exploration of the Open Targets Genetics Portal in situ. 2019-06-15 09:00:00 UTC 2019-06-15 00:00:00 UTC Gothenburg, Sweden Gothenburg Sweden [] [] [] workshops_and_courses [] Open Targets
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