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  • Bacterial Genomes: Comparative Genomics using Artemis Comparison Tool (ACT)

    11 November - 23 December 2019

    Bacterial Genomes: Comparative Genomics using Artemis Comparison Tool (ACT) https://tess.elixir-europe.org/events/bacterial-genomes-comparative-genomics-using-artemis-comparison-tool-act-003b5554-1cac-45b9-ae71-cf1656ab62a3 # Overview * **Duration**: 3 weeks, 5 hours per week * Free * Certificate of achievement available on satisfactory completion * **Start Date**: The course is run ‘live’ for 3 weeks from the start date above. Once this period is over there will be no live monitoring of the forums, but you can still join and complete the course during the remaining period. ### Why join the course? Disease outbreaks are still a big problem in our modern world. Comparison between two or more bacterial genomes can help improve understanding of the causes of pathogenicity and outbreaks of disease caused by bacteria. On this course you will learn how to use the free Artemis Comparison Tool (ACT). Developed at the Wellcome Sanger Institute, ACT will help you to visualise the comparison of genomes and analyse the results. ### Who is the course for? This course would benefit those interested in learning how to use tools to investigate and research bacterial genomes, and acquire bioinformatics skills to evaluate the role of microbial genes in disease. Learners will gain experience in comparative genomics, using the Artemis Comparison Tool to probe, visualise and compare genomes, and analyse the results. This course will be of interest to anyone interested in microbiology, including undergraduates, post-graduates, biomedical researchers, microbiologists, bioinformaticians, teachers, and healthcare professionals. The opportunity to gain experience in using the Artemis Comparison Tool, a computational tool designed for comparative genomics, will also be of interest to all those who have studied our pre-requisite courses: those with an interest in genomics and disease outbreaks, teachers and their 16-18-year-old science and computing students. Ideally, you will have completed [Bacterial Genomes: From DNA to Protein Function Using Bioinformatics][1] and [Bacterial Genomes: Accessing and Analysing Microbial Genome Data][2] before joining this course. [1]: /our-events/bacterial-genomes-dna-protein-function-bioinformatics-online-sep19/ [2]: /our-events/bacterial-genomes-accessing-analysing-microbial-genome-data-feb19/ # Programme ### What topics will you cover? Week 1 * Introduction to comparative genomics * Introduction to ACT Week 2 * Analyse available data * Generate your own comparison files * Make your own comparisons in ACT Week 3 * Identify pseudogenes in Mycobacterium leprae using ACT * Peer review project: Comparative genomics on two clinically relevant plasmids from Shigella ### What will you achieve? By the end of the course, you'll be able to... * Explain the advantages of comparative genomics * Explore basic tools of ACT * Interpret results from already generated comparison files * Produce new comparisons and analyse results * Develop hypothesis based on results observation ### What software or tools do you need? This course will give you an opportunity to learn about and use Artemis Comparison Tool (ACT), a free tool used to display pairwise comparisons between two DNA sequences. To run this software effectively, you will require a computer (Windows, Mac or Linux) with 2GB RAM. The current version of ACT requires version 11 of Java to run successfully. Java 11 can be downloaded from [this link][1]. Older versions of ACT require Java 8 to run successfully. Java 8 can be downloaded from [this link][2]. [1]: https://www.oracle.com/technetwork/java/javase/downloads/jdk11-downloads-5066655.html [2]: https://www.java.com/en/download/ # Educators ## Lead Educators ### Dr Anna Protasio I am a researcher in parasitology and life sciences. I am passionate about bioinformatics and how we can use these tools to answer questions in biology. ### Dr Christine Boinett I am a researcher in bacterial genetics and my interest is in understanding the development of resistance in bacterial pathogens using next generation sequencing techniques. ### Dr. Ulrike Böhme I am a researcher in parasitology at the Wellcome Sanger Institute where I work as biocurator for Plasmodium genomes. ### Dr. Pablo Tsukayama I am a professor of microbiology at Universidad Peruana Cayetano Heredia and a visiting research scholar at the Wellcome Sanger Institute. I study how pathogen populations evolve and spread in Peru. ### Martin Aslett I am the IT Manager for the Wellcome Genome Campus Advanced Courses and Scientific Conferences team. My interests lie in bioinformatics and its application to microbial genomics. ### Matthew Dorman I am a graduate student at the Wellcome Sanger Institute, where I research the virulence and the molecular genetics of bacterial pathogens as part of the Infection Genomics programme. ## Programme Lead Educator ### Professor Nicholas Thomson I am a Group Leader at the Wellcome Sanger Institute. I provide scientific oversight for this course. I am interested in bacterial evolution and the spread of infectious disease. # What's Included Wellcome Genome Campus Advanced Courses and Scientific Conferences are offering everyone who joins this course a free digital upgrade, so that you can experience the full benefits of studying online for free. This means that you get: * Unlimited access to this course * Includes any articles, videos, peer reviews and quizzes * Tests to validate your learning * A PDF Certificate of Achievement to prove your success when you’re eligible 2019-11-11 09:00:00 UTC 2019-12-23 23:59:59 UTC Wellcome Genome Campus - Advanced Courses [] advancedcourses@wellcomegenomecampus.org [] [] workshops_and_courses [] comparativegenomicsHDRUK
  • Assembly of long-read sequencing (2 days)

    12 - 13 November 2019

    Brisbane, Australia

    Assembly of long-read sequencing (2 days) https://tess.elixir-europe.org/events/assembly-of-long-read-sequencing-2-days-a1383ac8-7ceb-429e-9360-61be939cbcdb 2019-11-12 09:00:00 UTC 2019-11-13 17:00:00 UTC QFAB Brisbane, Australia Brisbane Australia Bioinformatics [] [] [] [] [] bioinformatics RNA-SeqGalaxy
  • RNA-Seq using R (2 days - Knowledge of R required)

    3 - 4 December 2019

    Brisbane, Australia

    RNA-Seq using R (2 days - Knowledge of R required) https://tess.elixir-europe.org/events/analysis-of-ngs-data-workshops-advanced-393853d7-8b13-4f51-b774-afb159f5d818 2019-12-03 09:00:00 UTC 2019-12-04 17:00:00 UTC QFAB Translational Research Institute, 37, Kent Street, Brisbane, Australia Translational Research Institute, 37, Kent Street Brisbane Brisbane City Australia Bioinformatics [] [] [] [] [] bioinformaticsGalaxy RNA-Seq
  • Introductory Linux Tutorial for Life Sciences 4

    10 - 12 December 2019

    Elixir node event
    Introductory Linux Tutorial for Life Sciences 4 https://tess.elixir-europe.org/events/introductory-linux-tutorial-for-life-sciences-4 NBIS (the Swedish node of ELIXIR) and ELIXIR Slovenia are offering an "Introduction to Linux" course targeted at life scientists who want to extend their skills and knowledge. Big data (usually in the form of large text files) are generated nowadays in many fields of science. Trying to handle this data with applications like Word or Excel is difficult or impossible, while using the Linux command line can improve data processing efficiency. Unix/Linux provides an excellent computing environment for several disciplines (such as bioinformatics, physics, engineering) and the command line interpreter (shell) serves as an interface to many big-data processing programs. The course provides a basic introduction to Unix/Linux commands and covers how Unix/Linux commands can be used to manage and inspect your data and results, and how to generate and run pipelines and workflows using basic shell scripting. Finally, we will show you how the command line is used for access to supercomputers for boosting your scientific research. Participants will be able to attend the course either by traveling to Stockholm or to Umeå in Sweden, to Ljubljana in Slovenia, or by connecting remotely via the ELIXIR Slovenia eLearning Platform (EeLP). The number of remote students is limited to 30. The number of students per classroom is limited to 15 for Stockholm and Umeå, and 20 for Ljubljana. Additional participants will be placed on a waiting list and contacted as soon as space becomes available. The course will be broadcast from Sweden. 2019-12-10 09:00:00 UTC 2019-12-12 17:00:00 UTC ELIXIR Sweden (NBIS) and ELIXIR Slovenia Bioinformatics Computer science NBISUniversity of Ljubljana, Faculty of Medicine [] Life Science ResearchersbioinformaticiansBiophysicistsengineers [] [] life sciences LinuxUnixEeLPeLearningCommand line
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