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  • RSS South West: Network Time Series

    No date given

    London, United Kingdom

    RSS South West: Network Time Series https://tess.elixir-europe.org/events/rss-south-west-network-time-series Speaker: Guy Nason (University of Bristol; Royal Statistical Society Vice President for Academic Affairs) Abstract: A network time series is a multivariate time series where the individual series are known to be linked by some underlying network structure. Sometimes this network is known a priori, and sometimes the network has to be inferred, often from the multivariate series itself. Network time series are becoming increasingly common, long, and collected over a large number of variables. We are particularly interested in network time series whose network structure changes over time. We describe some recent developments in the modeling and analysis of network time series via network autoregressive integrated moving average (NARIMA) process models. NARIMA models provide a network extension to a familiar environment that can be used to extract valuable information and aid prediction. As with classical ARIMA models, trend can impair the estimation of NARIMA parameters. The scope for trend removal is somewhat wider with NARIMA models and we exhibit some possibilities. We will illustrate the operation of NARIMA modeling on some real data sets. This is joint work with Kathryn Leeming (Bristol), Marina Knight (York) and Matt Nunes (Lancaster). Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Meet the statisticians: data support for the third sector

    No date given

    London, United Kingdom

    Meet the statisticians: data support for the third sector https://tess.elixir-europe.org/events/meet-the-statisticians-data-support-for-the-third-sector Do you have a project that would benefit from the skills of a statistician or data scientist? Want to speak to us about this project and be linked with a volunteer statistician who is willing to work pro bono? Then come along to our drop-in session for Statisticians for Society. The Royal Statistical Society (RSS) is inviting third sector organisations interested in pro bono support to spend time with our scoping panel and identify ways that volunteer statisticians can be involved in your project. If you are looking to make the most of your data, measure your impact or use data in decision making, then these ‘drop in’ sessions are a great opportunity for you to discuss what is possible and the expertise required to carry out the work. The Royal Statistical Society is the professional body for statisticians, data analysts and data scientists. Through Statisticians for Society, RSS fellows are offering their time and skills at no cost to help organisations collect, analyse and present data. Who should attend? Any UK registered charity or social purpose organisation with an annual turnover of/less than £1 million. If your charity or social purpose organisation does not meet our selection criteria, but wishes to attend, please contact Amaka Nwagbara and we can discuss if this initiative could directly help you. Timings You will be able to book to attend one of these four hour-long sessions: • 10.00am - 11.00am • 11.00am -  12.00pm • 1.00pm   -  2.00pm • 2.00pm   -  3.00pm Please note that registration is required and places are limited. To book your place, click the ‘Register Now’   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS Nigeria: Understanding the world through data

    No date given

    London, United Kingdom

    RSS Nigeria: Understanding the world through data https://tess.elixir-europe.org/events/rss-nigeria-understanding-the-world-through-data Data users need help in making sense of the overwhelming volume of data and information they are presented with every day. This can be accomplished by increasing collaboration across sectors and enhancing users’ skills. In addition, policymakers and the public in general must improve their data literacy The event will showcase the role of Statistics in achieving sustainable development goals.  We welcome confirmed speakers Professor T. O. Obilade from Department of Mathematics, Faculty of Science, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria and Professor K. S. Adekeye from Redeemer’s University, Ede, Osun State, Nigeria. The event is funded by Royal Statistical Society, London, England, United Kingdom in collaboration with Department of Statistics, College of Physical Sciences, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria, Oyo State Bureau of Statistics and Nigerian Institute of Science Laboratory Technology. All are welcome to attend the event, however, we ask that people register in advance for proper arrangement.   Many thanks Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • ESGI 145

    No date given

    London, United Kingdom

    ESGI 145 https://tess.elixir-europe.org/events/esgi-145 Across a five day workshop, the 145th European Study Group with Industry brings mathematicians and industrialists together to work side by side to solve the real and important issues that companies are facing today The ESGI is an exciting opportunity for students in academics to get hands on experience with a real problem in industry in a collaborative setting. Data analysis problems have gained more prominence at these conferences in recent years and we need more statisticians involved! Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • The use of simulation to support modern day needs of manufacturing companies - Making better decisions based on simulation

    No date given

    London, United Kingdom

    The use of simulation to support modern day needs of manufacturing companies - Making better decisions based on simulation https://tess.elixir-europe.org/events/the-use-of-simulation-to-support-modern-day-needs-of-manufacturing-companies-making-better-decisions-based-on-simulation This event will commence with an introductory talk on simulation and its application, followed by sharing of case studies and a practical workshop session. The aim of this workshop is to develop awareness and basic competence in the use of simulation to support modern day needs of manufacturing companies. Based on a real cases, this workshop will guide you on how to make better decisions based on discrete event simulation. Agenda                                                                • Basic concepts of simulation                            • Successful examples in manufacturing         • How to run a model?                           • How to build a simple model?  • Formulating a simulation problem • Final discussion and questions Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Symposium to Celebrate 50 Years of the MSc Medical Statistics

    No date given

    London, United Kingdom

    Symposium to Celebrate 50 Years of the MSc Medical Statistics https://tess.elixir-europe.org/events/symposium-to-celebrate-50-years-of-the-msc-medical-statistics Statistics as Alchemy: Turning data into gold Celebrating 50 years of the Masters in Medical Statistics 2019 is the 50th anniversary of the London School of Hygiene & Tropical Medicine MSc Medical Statistics: the first students graduated in 1969 when Peter Armitage was Professor of Medical Statistics. To celebrate, we warmly invite you to a 2-day symposium on 11-12 April. We are delighted by the line-up of stimulating speakers, ranging across causal inference, electronic health records, innovative trial designs and estimands. Peter Armitage has recorded a welcome message to start the meeting. The symposium includes the Bradford Hill Memorial Lecture which will be given by Michael Hughes (Harvard University) on 11 April. Other speakers confirmed so far include: Shadrac Agbla, Deborah Ashby, Nicky Best, James Carpenter, Nick Jewell, Ruth Keogh, Alan Phillips, Stuart Pocock, Linda Sharples, Liam Smeeth, Jonathan Sterne, Jenny Thompson, Stijn Vansteelandt. Equally importantly, it’s a great opportunity to catch up with friends and make new ones – not least at our 50th party on the evening of 11th April!     Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Interactive Visualisation in R

    No date given

    London, United Kingdom

    Interactive Visualisation in R https://tess.elixir-europe.org/events/interactive-visualisation-in-r-9ec0ca05-c2d0-461d-bd5b-58d9af75c8b1 Presented by Martin John Hadley Level - Professional CPD 12 hours This course will introduce two technologies that will fundamentally change your use of R for data presentation on the web: html widgets and Shiny. This course will show you how easy it can be to build interactive charts, maps, datatables with html widgets and how to quickly and easily build sophisticated interactive applications with Shiny.     Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Getting your views on plans to transform the UK’s population and migration statistics system (Roundtable event)

    No date given

    London, United Kingdom

    Getting your views on plans to transform the UK’s population and migration statistics system (Roundtable event) https://tess.elixir-europe.org/events/getting-your-views-on-plans-to-transform-the-uk-s-population-and-migration-statistics-system-roundtable-event Speakers: Centre for International Migration and Admin Data Census, ONS- Kerry Gadsdon Discussant: Madeleine Sumption (Migration Observatory)  About the Event:   Office for National Statistics (ONS) is transforming the way we produce population and migration statistics, to better meet the needs of our users. Working in partnership across the Government Statistical Service (GSS), we are progressing a programme of work to put administrative data at the core of our evidence on international migration (UK) and on population (England and Wales) by 2020.    Join us at this free interactive event, hosted by the Royal Statistical Society’s Official Statistics section in association with the Migration Statistics User Forum, where you can find out more about our latest research and give us your feedback on our developments and future plans.   Together we’ll discuss the following themes:   •    User needs: what do users of our statistics need to know about the population and how it changes over time? •    Concepts and definitions: what concepts should ONS statistics measure? What additional or alternative definitions would support you in better understanding population and patterns of migration?  •    Data sources: what data sources can we use to measure population and migration? •    Methods: what methods can we use to analyse administrative data?  •    Outputs: what outputs do we need to produce? What aspects of quality (timeliness, frequency, coherence, relevance, accuracy, accessibility and interpretability) are most important to you?   Programme:  1:00   Introduction/ aims for the afternoon 1:15   ONS presentation (Kerry Gadsdon) 1:35   Discussant (Madeleine Sumption)  1:55   Q&A/ Sli.do 2:20   Tea break  2:50   Discussion sessions 3:50/4:00 Feedback from the sessions 4:20    Wrap up/Future steps and Sli.do 4:30    Close  Refreshments: tea, coffee and biscuits will be available at 3 pm. Attendance is free and open to all, whether fellows of the RSS or not, but pre-registration is required.   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Bradford Hill Memorial Lecture

    No date given

    London, United Kingdom

    Bradford Hill Memorial Lecture https://tess.elixir-europe.org/events/bradford-hill-memorial-lecture The London School of Hygiene and Tropical Medicine & The Royal Statistical Society Medical Section Present: 2019 Bradford Hill Memorial Lecture Countering the HIV epidemic: statistical issues in treatment evaluation and policy Speaker: Dr Michael D. Hughes (Harvard T.H. Chan School of Public Health, Boston, MA.) Abstract: There has been remarkable progress in HIV treatment, changing HIV infection from being a more immediately life-threatening disease to a chronic disease.  Numerous treatments have been evaluated in a long sequence of non-inferiority clinical trials using a surrogate endpoint, and complexities have arisen at the interface of treatment and prevention.  Key policy questions included when during the course of the disease to start treatment, and the extent to which treatment recommendations can be population-based versus personalized.  Dr Hughes will describe some of the interesting statistical issues that have been addressed in advancing treatment for HIV infection. This lecture is free and open to the public, and will be followed by a reception in the South Courtyard Café. More information can be found here. Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Data Visualisation in the Popular Victorian Press

    No date given

    London, United Kingdom

    Data Visualisation in the Popular Victorian Press https://tess.elixir-europe.org/events/data-visualisation-in-the-popular-victorian-press Speaker: Dr Alison Hedley -  SSHRC Post-doctoral Research Fellow, McGill University About the Event: Dr Hedley writes “Most forms of data visualisation were encountered mainly by non-specialized readers for the first time in the nineteenth century. The primary medium through which these graphics circulated among mass audiences was the periodical. My postdoctoral research project, “Graphical Thinking: Data Visualisation in Popular British Periodicals, 1830-1910,” is a cultural and material history of the data graphics published in popular journalism. “Graphical Thinking” combines socio-historical analysis and close reading—the micro-analysis of specific print artifacts and genres—with a machine learning process known as image analytics—the macro-analysis of a digitized corpus of journalism. Investigating the publication history of data visualisations in general-audience newspapers and magazines such as the Times, the Illustrated London News, and the Strand, the project recovers an important but largely overlooked chapter in the history of mass visualisation literacy”. “In my presentation, I will discuss my project’s framework and methodology in relation to the nebulous field of data visualisation criticism. I will summarize ongoing case studies to illustrate the thrust of the project and its significance. Data graphics in mass digital journalism deploy many of the same visual practices as those established in the Victorian press. Given that the nineteenth-century history of popular data visualisation continues to shape how we communicate data for mass audiences, studying that history is essential to understanding the cultural functions of digital data graphics”.   Programme:  6.00 to 6:45pm: Author’s presentation  6:45 to 7.15pm: Q & A.   Refreshments alongside registration available from 5.30 pm Attendance is free and open to all, whether fellows of the RSS or not, but pre-registration is required.   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • The statistics of drug testing in sport

    No date given

    London, United Kingdom

    The statistics of drug testing in sport https://tess.elixir-europe.org/events/the-statistics-of-drug-testing-in-sport About the event: There have been a number of high-profile sports doping cases in recent years. Famous examples include the Russian Olympic scandal, Lance Armstrong, Justin Gatlin and many more. But how can cheating be distinguished from a good performance? How can abnormal measurements in drug tests be differentiated from measurement error? And how sure must the evidence be to punish athletes for failed drug tests? This event will bring together three experts in the field to discuss their experience in the statistics of drug testing. Following the presentations we will have an open discussion on the questions raised.    Speakers:  Professor Andrea Petroczi, Kingston University Dr Reid Aikin, World Anti-Doping Agency Professor Sheila Bird, Medical Research Council Biostatistics Unit, Cambridge Professor Don Berry, The University of Texas MD Anderson Cancer Center, Houston Event Fees: Fellows: Free  Non-Fellows: £25 Registration is required. Please register here: Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Setting national milestones for Wales – approaches and methods workshop

    No date given

    London, United Kingdom

    Setting national milestones for Wales – approaches and methods workshop https://tess.elixir-europe.org/events/setting-national-milestones-for-wales-approaches-and-methods-workshop About the event: The Well-being of Future Generations (Wales) Act 2015 sets out 7 well-being goals for Wales. In 2016 Welsh Government set 46 national indicators to track progress in achieving these goals. The Welsh Government are also required to set national milestones against the indicators that will help Ministers understand what progress is being made and whether we, as a nation, are on track. A consultation was launched in January to seek views on the criteria for setting milestones, and against which national indicators we should set milestones.  Once those indicators have been agreed, we will then involve experts, policymakers and stakeholders in setting the milestones.    This workshop session of the RSS South Wales Local Group, led by Welsh Government’s Chief Statistician, is to begin a discussion with statisticians and other experts to consider the possible approaches and the conceptual issues around setting milestones. For example, we may consider: •    What are the potential approaches, e.g absolute or relative measures and how should we decide which are most appropriate? •    How do we set milestones for datasets with a very limited amount of baseline data? •    How should statistical error be considered in setting milestones? •    What other statistical methods can be used to inform the setting of milestones? •    What time horizon would be most appropriate for setting national milestones? Attendance is free and open to all, whether fellows of the RSS or not, but pre-registration is required.   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS South Wales: Setting national milestones for Wales – approaches and methods workshop

    No date given

    London, United Kingdom

    RSS South Wales: Setting national milestones for Wales – approaches and methods workshop https://tess.elixir-europe.org/events/rss-south-wales-setting-national-milestones-for-wales-approaches-and-methods-workshop About the event: The Well-being of Future Generations (Wales) Act 2015 sets out 7 well-being goals for Wales. In 2016 Welsh Government set 46 national indicators to track progress in achieving these goals. The Welsh Government are also required to set national milestones against the indicators that will help Ministers understand what progress is being made and whether we, as a nation, are on track. A consultation was launched in January to seek views on the criteria for setting milestones, and against which national indicators we should set milestones.  Once those indicators have been agreed, we will then involve experts, policymakers and stakeholders in setting the milestones.    This workshop session of the RSS South Wales Local Group, led by Welsh Government’s Chief Statistician, is to begin a discussion with statisticians and other experts to consider the possible approaches and the conceptual issues around setting milestones. For example, we may consider: •    What are the potential approaches, e.g absolute or relative measures and how should we decide which are most appropriate? •    How do we set milestones for datasets with a very limited amount of baseline data? •    How should statistical error be considered in setting milestones? •    What other statistical methods can be used to inform the setting of milestones? •    What time horizon would be most appropriate for setting national milestones? Attendance is free and open to all, whether fellows of the RSS or not, but pre-registration is required.   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Intro to R

    No date given

    London, United Kingdom

    Intro to R https://tess.elixir-europe.org/events/intro-to-r-39dbef2e-6882-4975-a541-9fef905d185a Intro to R 26 April 2019 - Glasgow This is a one-day intensive course on R and assumes no prior knowledge. By the end of the course, participants will be able to import, summarise and plot their data.   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Data Carpentry

    No date given

    London, United Kingdom

    Data Carpentry https://tess.elixir-europe.org/events/data-carpentry-9564fc37-86ac-440e-8a14-7297e6778a08 Data Carpentry 30 April 2019 - Glasgow This course covers key aspects of the tidyverse, including dplyr, lubridate, tidyr and tibbles. It will help you take the pain out of data manipulation by leveraging the tidyverse. Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS Glasgow: Agent Based Modelling

    No date given

    London, United Kingdom

    RSS Glasgow: Agent Based Modelling https://tess.elixir-europe.org/events/rss-glasgow-agent-based-modelling Eric Silverman from the MRC/CSO Social and Public Health Sciences Unit at the University of Glasgow will present an introduction to agent based modelling and some practical applications. You’ll find more info here:https://drericsilverman.wordpress.com/ Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Programming in R

    No date given

    London, United Kingdom

    Programming in R https://tess.elixir-europe.org/events/programming-in-r-3d7ae26b-3e91-4f56-844f-125265587882 Programming in R 2 May 2019 - Glasgow One day course teaching fundamental techniques like functions for loops, conditional expressions and when to use them. Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Statistical Modelling

    No date given

    London, United Kingdom

    Statistical Modelling https://tess.elixir-europe.org/events/statistical-modelling Statistical Modelling 3 May 2019 - Glasgow     One day course teaching R’s fundamental modelling techniques, from hypotheses tests, ANVOA tables, regression analysis, to more sophisticated methods such as clustering and principal components analysis (PCA).  Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS Avon local group workshop: Challenges in local air pollution modelling

    No date given

    London, United Kingdom

    RSS Avon local group workshop: Challenges in local air pollution modelling https://tess.elixir-europe.org/events/rss-avon-local-group-workshop-challenges-in-local-air-pollution-modelling Speakers Enda Hayes - https://people.uwe.ac.uk/Person/EndaHayes Paula Moraga - https://paula-moraga.github.io/ Andrew Beddows - http://www.erg.kcl.ac.uk/research/home/ Bath Council (BANES) - https://www.bathnes.gov.uk/bath-breathes-2021-overview   Provisional Agenda:     13:15  Start and Introduction            Session One: Policy and Context 15:00  Coffee Break            Session Two: Statistics 17:00  Wrap Up 17:15 Wine and Networking   Attendance is free and open to all, whether fellows of the RSS or not, but pre-registration is required.     The workshop will take place in the 4 West building (Mathematical Sciences) which can be found on the parade, as shown on the map below:   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS South West: Challenges in ensuring that the evaluation of medical tests helps to improve patient health

    No date given

    London, United Kingdom

    RSS South West: Challenges in ensuring that the evaluation of medical tests helps to improve patient health https://tess.elixir-europe.org/events/rss-south-west-challenges-in-ensuring-that-the-evaluation-of-medical-tests-helps-to-improve-patient-health About the event Speaker: Jon Deeks, University of Birmingham Abstract: Health care organisations around the world need to make recommendations of the choice and provision of medical tests.  In 2018, the WHO for the first time, published the Essential Diagnostic Tests (the EDL) listing in vitro diagnostics which should be available around the world to ensure Universal Health Coverage. In doing so they have faced challenges in identifying evidence required to make rational decisions about test selection. Ideally medical tests, as with interventions, should be recommended for use when there is evidence that they do more good than harm. However, medical tests rarely directly improve patient outcomes - rather the medical interventions that are taken consequent on use of a test create benefit for patients – and it is rare to be able to obtain evidence that shows how tests save lives. Whilst evaluations of diagnostic or prognostic tests have typically focused on their accuracy to predict the numbers receiving appropriate or inappropriate treatment, extrapolating from these data to predict overall patient benefit is not always appropriate.  In this talk I will review challenges that health care organisations face in identifying evidence required to assess benefits and harms of testing, drawing on experience working with the WHO EDL. Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Webinar: MCP-Mod – Theory, Implementation and Extensions

    No date given

    London, United Kingdom

    Webinar: MCP-Mod – Theory, Implementation and Extensions https://tess.elixir-europe.org/events/webinar-mcp-mod-theory-implementation-and-extensions About the event MCP-Mod (Multiple Comparisons & Modelling) is a popular statistical methodology for model-based design and analysis of dose finding studies. This webinar will describe the theory behind MCP-Mod (plus extensions), and how to implement it within available software. Pantelis Vlachos (Cytel) will provide a brief introduction to the methodology and illustrate the MCP-MoD capabilities in EAST 6.5. Saswati Saha (Inserm, Aix-Marseille University) will discuss new variations and alternatives to MCP-Mod and show how to implement them in R. Neal Thomas (Pfizer) will present further technical details of MCP-Mod by evaluating the method using results from least squares linear model theory.   Abstracts: MCP-Mod in East®:  Early development dose-finding design and analysis Pantelis Vlachos - Cytel Inc.  Selection of a dose (or doses) to carry into a confirmatory phase III study is among the most difficult decisions in drug development. A prerequisite for informed decision making and dose selection at the end of phase II is a solid characterization of the dose-response relationship(s).The MCP-Mod method combines principles of multiple comparisons with modelling techniques to provide an efficient alternative to traditional dose-finding studies which are either designed and analyzed based on multiple comparisons of active doses vs placebo within an ANOVA framework, of assume a functional relationship between response and dose according to a certain parametric model. We illustrate MCP-Mod design and analysis capabilities with East®.   Understanding MCP-Mod dose finding as a method based on linear regression Neal Thomas - Pfizer Inc. MCP-MOD  is a testing and model selection approach utilizing contrast-based test statistics and p-values adjusted for multiple comparisons. The MCP-Mod procedure can be alternatively represented as a method based on simple linear regression, where 'simple' refers to the inclusion of an intercept and a single predictor variable, which is a transformation of dose. It is shown that the contrasts are equal to least squares linear regression slope estimates. The test for each contrast is the usual t-statistic for a null slope parameter, except that a variance estimate with fewer degrees of freedom is used in the standard error. Selecting the model corresponding to the most significant contrast p-value is equivalent to selecting the predictor variable yielding the smallest residual sum of squares. Many of the properties of MCP-Mod procedure can be understood and quantified using results from least squares linear model theory   Model based dose-finding methods in Phase II clinical trials Saswati Saha - Inserm, Aix-Marseille University    The primary objective of this presentation is to discuss dose-finding methods in Phase II clinical trials that can simultaneously establish the dose-response relationship and identify the right dose. MCP?Mod is one of the pioneer approaches developed within the last 10 years. Though MCP-Mod is identified as an efficient statistical methodology for model-based design and analysis of Phase II dose finding studies under model uncertainty, a major disadvantage of MCP-Mod is that the parameter values of the candidate models need to be pre-specified a priori for the PoC testing step. This may lead to loss in power and unreliable model selection. Off late several new variations and alternatives to MCP-Mod are explored where the parameter values need not be pre-specified in the PoC testing step and can be estimated after the model selection step. We will briefly introduce four such state-of-art dose-finding methods, show how to implement the methods in R software and present a numerical comparison between the different new methods and the MCP-Mod approach   Please click here to download the details. This webinar is free to attend. Please click here to register.                                   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS Leeds / Bradford: Solutions in Causal Inference

    No date given

    London, United Kingdom

    RSS Leeds / Bradford: Solutions in Causal Inference https://tess.elixir-europe.org/events/rss-leeds-bradford-solutions-in-causal-inference The RSS Medical Section and Leeds / Bradford Local Group present a joint session on Solutions in Causal Inference   Programme: 2:30-3:00 pm Kellyn Arnold, PhD student, School of Medicine, University of Leeds.  Do we fully understand the challenges of introducing machine learning into health research? Lessons from our (poor) understanding of linear modelling In health research, machine learning (ML) is often hailed as the new frontier of data analytics which, combined with big data, will purportedly revolutionise delivery of healthcare and ultimately lead to more informed public health policy and clinical decision-making. However, much of the promise of ML is predicated on prediction, which is fundamentally distinct from causal inference. Nevertheless, these two concepts are often conflated in practice. I’ll briefly consider the sources and consequences of this conflation in the context of generalised linear models, as well as the potential implications for ML methods. 3:00-3:40 pm Peter Tennant, University Academic Fellow in Health Data Science, Leeds Institute for Data Analytics, University of Leeds.  Analyses of change: A causal inference perspective Keynote speaker 4:00-5:00 pm Johannes Textor, Radboud University Medical Center, Nijmegen, The Netherlands & Visiting Associate Professor, LIDA, University of Leeds, UK. Making DAG-based causal inference more quantitative Directed acyclic graphs (DAGs) are sequential, discrete-time models data-generating processes. DAGs have become popular due to the principled and elegant fashion in which they allow to formalize causal inference. In model-based research, much attention is usually paid to the aspect of model checking -- testing whether a model actually fits the data it is supposed to describe. Specifically, models are often only considered credible after they have survived serious falsification attempts. Surprisingly, DAG models are rarely ever tested at present, and at least in Epidemiology there even appears to be a widely-held belief that DAG models should not be tested at all. In this talk, I will make the case that DAG model checking should be an integrated part of any DAG-based causal inference. I will explain how DAGs can be tested by means of the conditional independencies that they imply, how this can be done in practice with continuous and/or categorical data, which problems we are likely to encounter, and how to address these problems. I will also show how DAG testing methodology can be converted into a means to reason about the strengths of certain hypothesized pathways in a DAG.   Refreshments will be available from 2 pm, and there will be a short refreshment break before the keynote presentation. Attendance is free and open to all, whether fellows of the RSS or not but pre-registration is required.   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Characteristics of Good Data Governance

    No date given

    London, United Kingdom

    Characteristics of Good Data Governance https://tess.elixir-europe.org/events/characteristics-of-good-data-governance About the event: Ownership of datasets is at odds with respect for people, and good use of the data, similarly individual control. Data governance is the obvious solution yet obviously lacking in current data sharing activities. However, there are good practices, many of which seem to be specialised to specific settings. This meeting will bring together speakers from quite different areas to expound their view. We expect speakers to identify problems which have led to their view, as well as strengths of their own practices. These views are likely to be challenging and we expect to see some contradictions and remaining unresolved problems. But we also hope to develop consensus on the characteristics of good data governance, and any contrasts with practice. This will lead to consideration of capacity and capability to deliver this, which seems to be acutely short, and therefore an imperative for this to be resolved. Anyone interested in contributing to the agenda of resolving the contemporary challenge of data governance will be very welcome at the meeting will need to form an agenda for the future development of data governance. Chair: Hetan Shah - Royal Statistical Society (policy/ethics overview)   Speakers: Peter Wells (Open Data Institute) - "Data trusts (and other approaches to stewardship)" Catherine Bromley (UK Statistics Authority) - “Building confidence in the handling and use of data” Max Tse (National Audit Office) - "Data and Transformation" Madeleine Murtagh (Newcastle University) - “Developing responsive, collective data governance for health research” Paul Burton (Newcastle University) -  “DataSHIELD: taking the analysis to the data” Wendy Craig (Newcastle University) - "Data Protection Data Ethics" Kieron O'Hara (University of Southampton) - “Data Trusts, Governance and Ethics: A Functional View” Robin Rice (Edinburgh University) - "Providing support and services for researchers in good data governance" Steve Caughey (National Innovation Centre for Data) - "Encouraging Data Sharing: A practical approach"      With the support of:   Attendance is free and open to all, but pre-registration is required     Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS Merseyside - Mental Health Statistics

    No date given

    London, United Kingdom

    RSS Merseyside - Mental Health Statistics https://tess.elixir-europe.org/events/rss-merseyside-mental-health-statistics On the 13th May 2019, the RSS Merseyside Local Group will welcome speakers Professor Richard Emsley (Kings College London), and Dr Anais Rouanet (MRC Biostatistics Unit, Cambridge University) for our event "Mental Health Statistics: Showcasing the analysis of mental health data", which coincides with the UK Mental Health Awareness Week.  The meeting will take place in Room 107, Brodie Tower, University of Liverpool Campus (Building 233, in gridsquare C8 on campus map, https://www.liverpool.ac.uk/files/docs/maps/liverpool-university-campus-map.pdf) 14:00-14:50 Dr Anais Rouanet (MRC Biostatistics Unit, Cambridge University): Clustering methods for the study of cognitive decline and dementia for precision medicine: applications to French and US cohorts. Dementia is one of the major causes of dependency amongst the elderly. No treatments have proved efficient to slow down the progression of this syndrome as they are probably administered too late. Identifying subjects at high risk of dementia is thus essential to start patient management earlier and improve individual health care, in a precision medicine context. Clustering methods are a powerful tool to identify and profile the at-risk population over time. A first application will be based on the North American ADNI cohort, using a nonparametric Bayesian clustering method to identify patterns of cognitive declines, associated with brain imaging profiles. In a risk-stratified approach, a joint latent class model will be considered to analyze simultaneously the time-to-dementia in the French Paquid study, to associate different risks of dementia to each cognitive pattern, giving a more clinical interpretation to the clusters. This method accounts in particular for the interval censoring of dementia diagnosis as well as the competing risk of death. Finally, a dynamic prediction tool will be derived, allowing to compute for a given subject, the probability to develop dementia within the next 5 years, based on cognitive tests. This probability can then be updated at each new marker value collected. These statistical tools are thus promising to refine the stratification of subjects with high risk of dementia and ultimately develop individual dynamic predictive tools for dementia, to improve individual care and/or for recruitment in clinical trials. 14:50-15:10 Tea and Coffee break 15:10-16:00 Professor Richard Emsley (Kings College London): How do mental health interventions work and who do they work for? Well-designed randomised trials should involve examining the intermediate pathways through which the intervention under study affects the outcome. Similarly, in observational studies understanding how exposures impact on later outcomes is of crucial importance. Both of these questions can be answered using an approach called mediation analysis. This talk will discuss some of our new statistical methodology in mediation analysis arising from our research programme in efficacy and mechanisms evaluation. We illustrate these methods with examples from the field of mental health, examining the mediating role of various cognitive processes in the effect of childhood trauma on symptoms of psychosis and the role of sleep in psychological well-being. All are welcome to attend the meeting, however we ask that people register in advance so that we can organise sufficient refreshments.  More information, and registration links can be found at  https://sites.google.com/site/rssmerseyside/research-meetings/mentalhealthstatistics . Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS Sheffield: Uses of R Software

    No date given

    London, United Kingdom

    RSS Sheffield: Uses of R Software https://tess.elixir-europe.org/events/rss-sheffield-uses-of-r-software Putting the R in Reproducible Research - Anna Krystalli (Research Software Engineering, The University of Sheffield) R and its ecosystem of packages offers a wide variety of statistical and graphical techniques and is increasing in popularity as the tool of choice for data analysis in academia. In addition to its powerful analytical features, the R ecosystem provides a large number of tools and conventions to help support more open, robust and reproducible research. This includes tools for managing research projects, building robust analysis workflows, documenting data and code, testing code and disseminating and sharing analyses. In this talk we’ll take a whistle-stop tour of the breadth of available tools, demonstrating the ways R and the Rstudio integrated development environment can be used to underpin more open reproducible research and facilitate best practice. Cloud Computing with R - Alison Parton (Animal and Plant Sciences, The University of Sheffield) R has cemented itself as the language of choice for many a statistician and data scientist, but is often heckled as a sluggish competitor to the likes of Python. This talk will discuss one avenue for maintaining the comfort and power of R (see Anna’s talk!) without having to wait days for your desktop analysis to complete. The foreach package is a set of functions that allow virtually anything that can be expressed as a for-loop as a set of parallel tasks. By registering a parallel backend through the doParallel package, you can speed up the run-time of your work by utilising the full capacity of your machine. Alison will introduce how to rewrite workflows to utilise the foreach approach and show how you can implement a parallel workflow on your own machine with doParallel. For a low-range machine, this will reduce your run-time by 4-fold and for those lucky few with high-range budgets you’ll receive something around 16-fold. So how about going one step further, and increasing to hundreds-fold? We can achieve this by using cloud computing services, taking the load away from your own machine. Cloud computing services have been seen to have a steep learning curve and this has led to many shying away from using such a useful resource. Alison will introduce you to the doAzureParallel package for R, create by Microsoft to bypass this learning curve and allow you to implement the foreach package in parallel in the cloud with only minor amendments to the R code that has been blighting you for months.  R Validation Hub Project - Lyn Taylor (Phastar, PSI AIMS SIG Lead, RSS Local Group chair) To date, the use of R Software in the pharmaceutical industry has been relatively limited to exploratory work and not routinely used in regulatory submissions where SAS® Software is still favoured. One of the difficulties in using R for submissions is being able to provide the regulators with appropriate documentation of testing and validation for the packages used. In June 2018, the R consortium granted funding for a PSI AIMS SIG initiative to create an online ‘R package validation repository’. With representatives from Abbvie, Amgen, Biogen, Eli Lilly, FDA, GSK, J&J, Merck, Merck KGaA, Novartis, PPD, PRA, Pfizer, Roche / Genentech, Syne qua non and the Transcelerate project, the ‘R Validation Hub’ team launched a free to access web site to host validation documentation and metrics for R packages (https://www.pharmar.org/). Although, the project is still in its early stages, it is looking to expand on the website content and encourage contribution of R metrics and tests for packages from all R-users. The talk will discuss what is meant by validation, how R differs to SAS, justify our approach to the validation issue and present the future capabilities of the website and how all R-users are set to benefit from the work. Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Introduction to R & Statistical Modelling in R

    No date given

    London, United Kingdom

    Introduction to R & Statistical Modelling in R https://tess.elixir-europe.org/events/introduction-to-r-statistical-modelling-in-r-42ff19ae-30dc-49f5-95eb-ffa4f5d923d3 Presented by Dr Colin Gillespie / Dr Jamie Owen Level - Foundation CPD 12 hours This two day course focuses on entering, working with and visualising data (Day 1), as well as regression modelling in R, including linear, general logistic and survival models (Day 2). Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS South Wales: New Innovations in Healthcare Analytics

    No date given

    London, United Kingdom

    RSS South Wales: New Innovations in Healthcare Analytics https://tess.elixir-europe.org/events/rss-south-wales-new-innovations-in-healthcare-analytics About the event: The healthcare sector has witnessed largescale technological change in recent years, including in the area of data analysis. The digitalisation of health records has opened the door for the application of advanced analytical techniques, leading to improved decision-making and patient outcomes. However, these innovate approaches have introduced new challenges, particularly around how the methods are implemented in practice and how their outputs are explained to users. This event, hosted by the RSS South Wales Local Group, consists of three talks on a variety of subjects, and brings together speakers from academia, the public sector, and commercial research. There will be an opportunity for networking between and following the talks, and light refreshments will be provided. Speakers:  Professor Alexander Balinsky, Cardiff University School of Mathematics Mathematics of Deep Learning Dr Tracey England, Aneurin Bevan Continuous Improvement (ABCi) Modelling Unit Bringing Statistics into an NHS Setting Professor Phil McEwan, Managing Director of Health Economics & Outcomes Research Ltd. Data Analytics in Health Economics and Outcomes Research   Full Abstracts available here Attendance is free and open to all, whether fellows of the RSS or not, but pre-registration is required.       Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • RSS West Midlands: Modelling genes: the backwards and forwards of mathematical population genetics

    No date given

    London, United Kingdom

    RSS West Midlands: Modelling genes: the backwards and forwards of mathematical population genetics https://tess.elixir-europe.org/events/rss-west-midlands-modelling-genes-the-backwards-and-forwards-of-mathematical-population-genetics Speaker: Alison Etheridge OBE FRS - University of Oxford   About the Event: When Mendelian genetics was rediscovered at the beginning of the 20th Century, it was widely believed to be incompatible with Darwin's theory of natural selection. The mathematical sciences, in the hands of pioneers such as Fisher, Haldane and Wright, played a fundamental role in the reconciliation of the two theories, and the new field of theoretical population genetics was born. But fundamental questions remained (and remain) unresolved. The genetic composition of a population can be changed by natural selection, mutation, mating, and other genetic, ecological and evolutionary mechanisms. How do they interact with one another, and what was their relative importance in shaping the patterns that we see today? Whereas the pioneers of the field could only observe genetic variation indirectly, by looking at traits of individuals in a population, researchers today have direct access to DNA sequences, but making sense of this wealth of data presents a major scientific challenge and mathematical models play a decisive role. In this lecture we'll discuss how to distill our understanding into workable models and then explore the remarkable power of simple mathematical caricatures in interrogating modern genetic data.   Attendance is free and open to all, but pre-registration is required:   Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Industrial Strength Data Science presents: “We are not unicorns”

    No date given

    London, United Kingdom

    Industrial Strength Data Science presents: “We are not unicorns” https://tess.elixir-europe.org/events/industrial-strength-data-science-presents-we-are-not-unicorns About the event: We, data scientists, have been objectified from early days… starting in 2012 when HBR called a data scientist “the sexiest job of 21st century” through to all the tales of business success driven by the buzz of big data. Especially firms who adopted some form of ML driven products started to spread tales about them, the unicorns. People who can come to your business and completely transform it. Has this done damage or favour to the data science industry? We are going to explore this topic in this indeed unique event hosted by Data Science Section of the Royal Statistical Society.  The event is going to be opened by Martin Goodson, the new chair of the section introducing what the section is planning over the next year. Magda Piatkowska (head of data solutions at the BBC) will be joined by renowned industry professionals, who have built teams and educated new generations of the data science professionals. Expect no unicorns, just debate.   This event is free and open to all, members and non-members, but registration is required.   This event will be followed by a drinks reception sponsored by Evolution AI and Mango Solutions                                                     Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
  • Standing up for Science workshop

    No date given

    London, United Kingdom

    Standing up for Science workshop https://tess.elixir-europe.org/events/standing-up-for-science-workshop About the event We are delighted to be running our Standing up for Science workshop for the first time in Norwich this year. Join us to find out how to make your voice heard in public debates about science.  Meet researchers who have engaged with the media or politicians, learn from respected science journalists, find out how researchers can inform policymakers,  get hints and tips from communications experts, and find out how to involve the public in communicating research. Click HERE for application details.  Deadline for applications: 17:00 on Wednesday, 17th April.     Royal Statistical Society The Royal Statistical Society, London, United Kingdom The Royal Statistical Society London United Kingdom EC1Y 8LX [] [] [] workshops_and_courses [] []
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