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  • Proteomics and Metabolomics with OpenMS

    27 - 29 April 2020

    Boston, United States of America

    Proteomics and Metabolomics with OpenMS https://tess.elixir-europe.org/events/openms-proteomics-and-metabolomics-course Educators: Oliver Kohlbacher, Julianus Pfeuffer, Timo Sachsenberg (CIBI), assisted by Oliver Alka Date: April 27 - April 29 Location: Northeastern University 315 and 320 Shillman Hall 115 Forsyth Street, Boston, Massachusetts 02115, USA Keynote Speakers: Oliver Kohlbacher Contents: The course introduces key concepts of non-targeted label-free proteomics and metabolomics. Non-targeted methods are ideal for unbiased discovery studies and scale well for large-scale studies (e.g., clinical proteomics/metabolomics). Based on example datasets we will then introduce several open-source software tools for proteomics and metabolomics, primarily focusing on OpenMS (www.OpenMS.org). We will demonstrate how these tools can be combined into complex data analysis workflows including visualization of results. Participants will have the opportunity to bring their own data and design custom analysis workflows together with instructors. Target audience: Target audience are experimental scientists with experience in proteomic and/or metabolomic research. We also welcome computational scientists interested in working with raw mass spectrometric data. Software Requirements: The participants should bring their own laptop computers. Instructions regarding downloading and installing all required software (Windows, OSX, or Linux) will be provided prior to the course. Installer versions of all required software will be available. Keywords: LC-MS based proteomics and metabolomics, OpenMS, workflows, KNIME, data analysis Tools: OpenMS, KNIME 2020-04-27 09:00:00 UTC 2020-04-29 17:00:00 UTC de.NBI Boston, Boston, United States of America Boston Boston Suffolk County United States of America [] [] [] workshops_and_courses [] []
  • Phylogenetic reconstruction course 2020

    20 May 2020

    Kiel, Germany

    Phylogenetic reconstruction course 2020 https://tess.elixir-europe.org/events/phylogenetic-reconstruction-course-2020 Educators: Tal Dagan (CAU) Date: 20.05.2019, 08:15 - 16:00 Location: Kiel Contents/Learning goals: The evolutionary history of genes or species is best studied and described by phylogenetic trees. The accumulating sequence data enable the reconstruction of phylogenetic trees for many diverse gene and species. A robust phylogeny is helpful in identifying phyletic groups as well as ancestral relations in the data and lateral gene transfer. Notwithstanding phylogenetic reconstruction is sensitive to various biases in the analysis that originate in alignment and phylogenetic reconstruction artifacts. Students in the workshop will learn to reconstruct multiple sequence alignment and phylogenetic trees of focal sequences. This includes a quantification of possible biases in the phylogenetic reconstruction and ways to counteract their influence on the results. In addition, the students will learn how to identify the root of phylogenetic trees and extract ancestral-descendent relations. The workshop is intended to address scientists from undergraduate to postdoc level and does not expect previous experience in phylogenetics. Basic knowledge on how to work with Linux will be advantageous. Prerequisites: None Keywords: Tree phylogeny, gene homology, rooting, robustness Tools: MAFFT, Guidance, PhyML, IQTree, MAD rooting, FigTree. 2020-05-20 09:00:00 UTC 2020-05-20 17:00:00 UTC de.NBI Kiel, Kiel, Germany Kiel Kiel Germany [] [] [] workshops_and_courses [] []

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