GATK Best Practices for Variant Discovery
17 - 19 July 2017
Edinburgh, United KingdomGATK Best Practices for Variant Discovery https://genomics.ed.ac.uk/services/gatk-best-practises-variant-discovery https://tess.elixir-europe.org/events/gatk-best-practices-for-variant-discovery This workshop will focus on the core steps involved in calling variants with the Broad’s Genome Analysis Toolkit, using the Best Practices developed by the GATK team. You will learn why each step is essential to the variant discovery process, what are the operations performed on the data at each step, and how to use the GATK tools to get the most accurate and reliable results out of your dataset. In the course of this workshop, we highlight key functionalities such as the GVCF workflow for joint variant discovery in cohorts, RNAseq-specific processing, and somatic variant discovery using MuTect2. We also preview capabilities of the upcoming GATK version 4, including a new workflow for CNV discovery, and we demonstrate the use of pipelining tools to assemble and execute GATK workflows. 2017-07-17 09:00:00 UTC 2017-07-19 17:00:00 UTC The King's Buildings, The University of Edinburgh, Edinburgh, United Kingdom The King's Buildings, The University of Edinburgh Edinburgh United Kingdom Bioinformatics Genomics Edinburgh Genomics Bert Overduin - email@example.com   workshops_and_courses  Variant discoveryGenomicsBioinformatics
Introduction to ChIP-seq Data Analysis and Visualisation using Ensembl
23 - 24 November 2017
Edinburgh, United KingdomIntroduction to ChIP-seq Data Analysis and Visualisation using Ensembl https://genomics.ed.ac.uk/services/introduction-chip-seq-data-analysis https://tess.elixir-europe.org/events/introduction-to-chip-seq-data-analysis-and-visualisation-using-ensembl-d125d464-c708-4919-8322-19d50246c22d ChIP-seq (Chromatin ImmunoPrecipitation followed by Sequencing) is a popular high-throughput sequencing assay to identify binding sites of DNA-associated proteins and histone modifications. Determining how proteins interact with DNA and the epigenetic landscape is essential for elucidating the regulation of gene expression. The aim of this workshop is to familiarise the participants with the primary analysis of ChIP-seq data sets by providing a balanced set of lectures and practicals on analysis methodologies. Practicals include publicly available ChIP-seq datasets, processed using widely used and open-source software programs (e.g. FASTQC, BWA, samtools, bedtools, wiggletools, MACS2, MEME, TOMTOM, ngsplot) and visualised on the Ensembl genome browser. 2017-11-23 09:00:00 UTC 2017-11-24 17:00:00 UTC The King's Buildings, The University of Edinburgh, Edinburgh, United Kingdom The King's Buildings, The University of Edinburgh Edinburgh United Kingdom EH9 3JN Genomics ChIP-seq Bioinformatics Edinburgh Genomics Bert Overduin - firstname.lastname@example.org   workshops_and_courses  BioinformaticsChIP-seqGenomics
Linux for Genomics
1 October 2018
Edinburgh, United KingdomLinux for Genomics https://genomics.ed.ac.uk/services/linux-genomics https://tess.elixir-europe.org/events/linux-for-genomics-4e98de3e-0102-46ab-9720-22f1122fd31d Genomic studies produce vast amounts of data, usually in the form of very large text files. Linux is particularly suited to working with such files, and is therefore arguably one of the most important tools in a bioinformatician’s toolkit. The Linux command-line enables one to view, filter and manipulate large text files that are difficult or impossible to handle with applications like Word or Excel, write pipelines to perform certain tasks, and run bioinformatics software for which no web interface is available. In this workshop we will first cover the most used Linux commands, followed by a short introduction to several popular command-line tools that were especially developed for genomics as well as file formats commonly used in genomics (BED, FASTA, FASTQ, GFF/GTF, SAM/BAM, VCF). 2018-10-01 09:00:00 UTC 2018-10-01 17:00:00 UTC The King's Buildings, The University of Edinburgh, Edinburgh, United Kingdom The King's Buildings, The University of Edinburgh Edinburgh United Kingdom EH9 3JN Genomics Bioinformatics Edinburgh Genomics Donald Dunbar - email@example.com   workshops_and_courses  BioinformaticsGenomicsLinux
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