Open Targets Platform

The Open Targets Platform is comprehensive and robust data integration resource for access and visualisation of biological and chemical data for drug target identification, disease biology, translational research and innovation. The open source Platform is one of the resources of the Open Targets consortium (https://www.opentargets.org/), a public-private partnership that uses human genetics, omics and chemical data for systematic drug target identification and prioritisation.

Open Targets Platform https://tess.elixir-europe.org/content_providers/open-target The Open Targets Platform is comprehensive and robust data integration resource for access and visualisation of biological and chemical data for drug target identification, disease biology, translational research and innovation. The open source Platform is one of the resources of the Open Targets consortium (https://www.opentargets.org/), a public-private partnership that uses human genetics, omics and chemical data for systematic drug target identification and prioritisation. /system/content_providers/images/000/000/096/original/open_targets.png?1530288094
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  • Bioinformatics for Discovery

    23 January 2019

    United Kingdom

    Bioinformatics for Discovery https://tess.elixir-europe.org/events/bioinformatics-for-discovery-f51fe25c-6f52-4589-b79c-5f829803f89a In this 90 min long tutorial, we will introduce the Open Targets and its other tools to aid drug target identification and prioritisation. This workshop is part of the Bioinformatics for Discovery course and is aimed at bench biologists working in the area of discovery science who want to learn more about bioinformatics tools and resources. No prior knowledge of bioinformatics is required and no experience of programming or the use of Unix / Linux is necessary. . 2019-01-23 09:00:00 UTC 2019-01-23 00:00:00 UTC Hinxton, United Kingdom Hinxton United Kingdom [] [] [] workshops_and_courses [] Open Targets
  • EMBL-EBI Intro to multiomics data integration

    14 February 2019

    United Kingdom

    EMBL-EBI Intro to multiomics data integration https://tess.elixir-europe.org/events/embl-ebi-intro-to-multiomics-data-integration In this 1 hour tutorial, we will highlight how the Open Targets integrates genetics, genomics, drug information and literature in a single web portal, the Open Targets Platform . This workshop is part of the EMBL-EBI Intro to multiomics data integration course and is imed at biologists who have some experience of working with at least one type of omics data, and computational biologists/bioinformaticians who wish to gain a better understanding of the biological challenges when working with integrated datasets. No programming or command line experience is required to attend this course. 2019-02-14 09:00:00 UTC 2019-02-14 00:00:00 UTC Hinxton, United Kingdom Hinxton United Kingdom [] [] [] workshops_and_courses [] Open Targets
  • Workshop at ASHG (Sold-out)

    18 October 2018

    San Diego, United States of America

    Workshop at ASHG (Sold-out) https://tess.elixir-europe.org/events/workshop-at-ashg In this workshop, we will introduce Open Targets Genetics Portal as part of the Open Targets ecosystem, highlighting variant-centric statistical evidence for prioritizing candidate causal variants at trait-associated loci, and identifying potential drug targets. We will present POSTGAP, a pipeline which merges genetic associations curated from literature with functional genomics, epigenetic and expression data (e.g., eQTL, promoter capture Hi-C, DNase hypersensitivity sites, regulatory elements) to resolve association signals at a locus and link each variant to its target gene(s) using a single evidence score. The portal also incorporates pre-computed fine-mapping at trait-associated loci across hundreds of UK Biobank phenotypes as well as cross-trait colocalization, furthering drug repurposing opportunities. This workshop will enable you to effectively use Open Targets Genetics to gain biological insight, prioritize genes, and inform target decision-making. Intended Audience: Attendees interested in the translational application of genetics and genomics with an emphasis on the identification of target genes of trait-associated loci, drug target identification, prioritisation and repurposing. Participants should bring their laptops for exploration of the Open Targets Genetics Portal in situ. 2018-10-18 09:00:00 UTC 2018-10-18 00:00:00 UTC San Diego, San Diego, United States of America San Diego San Diego San Diego County United States of America [] [] [] workshops_and_courses [] Open Targets
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